Schlom, Jeffrey

Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

Reits, E. A., Hodge, J. W., Herberts, C. A., Groothuis, T. A., Chakraborty, M., K.Wansley, E., Camphausen, K., Luiten, R. M., de Ru, A. H., Neijssen, J., et al. (2006) · The Journal of Experimental Medicine

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 1,737

Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide

Lutsiak, M. E. C., Semnani, R. T., De Pascalis, R., Kashmiri, S. V. S., Schlom, J., & Sabzevari, H. (2005) · Blood

T-cell and B-cell ImmunologyImmunotoxicology and immune responses

Cited by 903

Phase I Trial of M7824 (MSB0011359C), a Bifunctional Fusion Protein Targeting PD-L1 and TGFβ, in Advanced Solid Tumors

Strauss, J., Heery, C. R., Schlom, J., Madan, R. A., Cao, L., Kang, Z., Lamping, E., Marté, J. L., Donahue, R. N., Grenga, I., et al. (2018) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersTGF-β signaling in diseases

Cited by 406

Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses

SPIEGELMAN, S., BURNY, A., DAS, M. R., KEYDAR, J., SCHLOM, J., TRAVNICEK, M., & WATSON, K. (1970) · Nature

T-cell and Retrovirus StudiesViral-associated cancers and disorders

Cited by 292

Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer Models

Greene, S., Robbins, Y., Mydlarz, W. K., Huynh, A. P., Schmitt, N. C., Friedman, J., Horn, L. A., Palena, C., Schlom, J., Maeda, D. Y., et al. (2020) · Clinical Cancer Research

Immune cells in cancerImmune Cell Function and Interaction

Cited by 280

Dual targeting of TGF-β and PD-L1 via a bifunctional anti-PD-L1/TGF-βRII agent: status of preclinical and clinical advances

Lind, H., Gameiro, S. R., Jochems, C., Donahue, R. N., Strauss, J., Gulley, J. L., Palena, C., & Schlom, J. (2020) · Journal for ImmunoTherapy of Cancer

Cancer Immunotherapy and BiomarkersTGF-β signaling in diseases

Cited by 247

Viral vector-based therapeutic cancer vaccines

Larocca, C., & Schlom, J. (2011) · The Cancer Journal

Immunotherapy and Immune ResponsesVirus-based gene therapy research

Cited by 222

Simultaneous Detection of Reverse Transcriptase and High Molecular Weight RNA Unique to Oncogenic RNA Viruses

Schlom, J., & Spiegelman, S. (1971) · Science

T-cell and Retrovirus StudiesViral-associated cancers and disorders

Cited by 211

Synthetic DNA–RNA Hybrids and RNA–RNA Duplexes as Templates for the Polymerases of the Oncogenic RNA Viruses

SPIEGELMAN, S., BURNY, A., DAS, M. R., KEYDAR, J., SCHLOM, J., TRÁVNÍČEK, M., & WATSON, K. (1970) · Nature

DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms

Cited by 210

M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

Knudson, K. M., Hicks, K. C., Luo, X., Chen, J.-Q., Schlom, J., & Gameiro, S. R. (2018) · OncoImmunology

Cancer Immunotherapy and BiomarkersTGF-β signaling in diseases

Cited by 195

A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells

David, J. M., Dominguez, C., McCampbell, K. K., Gulley, J. L., Schlom, J., & Palena, C. (2017) · OncoImmunology

TGF-β signaling in diseasesCancer Immunotherapy and Biomarkers

Cited by 180

Immunotherapy with Autologous, Human Dendritic Cells Transfected with Carcinoembryonic Antigen mRNA: ORIGINAL ARTICLE

Morse, M. A., Nair, S. K., Mosca, P. J., Hobeika, A. C., Clay, T. M., Deng, Y., Boczkowski, D., Proia, A., Neidzwiecki, D., Clavien#, P.-A., et al. (2003) · Cancer Investigation

Immunotherapy and Immune ResponsesBacterial Cancer Therapy

Cited by 177

DNA-directed DNA Polymerase Activity in Oncogenic RNA Viruses

SPIEGELMAN, S., BURNY, A., DAS, M. R., KEYDAR, J., SCHLOM, J., TRAVNICEK, M., & WATSON, K. (1970) · Nature

DNA and Nucleic Acid ChemistryHepatitis B Virus Studies

Cited by 170

RNA-dependent DNA Polymerase Activity in Virus-like Particles isolated from Human Milk

SCHLOM, J., SPIEGELMAN, S., & MOORE, D. (1971) · Nature

T-cell and Retrovirus StudiesInfectious Diseases and Mycology

Cited by 157

Phase i trial of a recombinant yeast-CEA vaccine (GI-6207) in adults with metastatic CEA-expressing carcinoma

Bilusic, M., Heery, C. R., Arlen, P. M., Rauckhorst, M., Apelian, D., Tsang, K. Y., Tucker, J. A., Jochems, C., Schlom, J., Gulley, J. L., et al. (2014) · Cancer Immunology, Immunotherapy

Immunotherapy and Immune ResponsesBacterial Cancer Therapy

Cited by 102

Generation of Stable CD4+and CD8+T Cell Lines from Patients Immunized withrasOncogene-Derived Peptides Reflecting Codon 12 Mutations

Abrams, S. I., Khleif, S. N., Bergmann-Leitner, E. S., Kantor, J. A., Chung, Y., Hamilton, J. M., & Schlom, J. (1997) · Cellular Immunology

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 91

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

Hicks, K. C., Chariou, P. L., Ozawa, Y., Minnar, C. M., Knudson, K. M., Meyer, T. J., Bian, J., Cam, M., Schlom, J., & Gameiro, S. R. (2021) · Nature Communications

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 83

Cooperative immune-mediated mechanisms of the HDAC inhibitor entinostat, an IL15 superagonist, and a cancer vaccine effectively synergize as a novel cancer therapy

Hicks, K. C., Knudson, K. M., Lee, K. L., Hamilton, D. H., Hodge, J. W., Figg, W. D., Ordentlich, P., Jones, F. R., Rabizadeh, S., Soon-Shiong, P., et al. (2020) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 44

A pilot safety trial investigating a vector-based vaccine targeting carcinoembryonic antigen in combination with radiotherapy in patients with gastrointestinal malignancies metastatic to the liver

Gulley, J. L., Madan, R. A., Tsang, K.-Y., Arlen, P. M., Camphausen, K., Mohebtash, M., Kamrava, M., Schlom, J., & Citrin, D. (2011) · Expert Opinion on Biological Therapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 26

Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis

Robbins, Y., Friedman, J., Clavijo, P. E., Sievers, C., Bai, K., Donahue, R. N., Schlom, J., Sinkoe, A., Abdul Sater, H., Gulley, J. L., et al. (2021) · Journal for ImmunoTherapy of Cancer

Cancer Immunotherapy and BiomarkersHead and Neck Cancer Studies

Cited by 17