Gaisano, Herbert Y.

Impaired Gene and Protein Expression of Exocytotic Soluble N -Ethylmaleimide Attachment Protein Receptor Complex Proteins in Pancreatic Islets of Type 2 Diabetic Patients

Ostenson, C.-G., Gaisano, H., Sheu, L., Tibell, A., & Bartfai, T. (2006) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 232

Inhibition of Cholesterol Biosynthesis Impairs Insulin Secretion and Voltage-Gated Calcium Channel Function in Pancreatic β-Cells

Xia, F., Xie, L., Mihic, A., Gao, X., Chen, Y., Gaisano, H. Y., & Tsushima, R. G. (2008) · Endocrinology

Pancreatic function and diabetesCellular transport and secretion

Cited by 132

Syntaxin 1A Binds to the Cytoplasmic C Terminus of Kv2.1 to Regulate Channel Gating and Trafficking

Leung, Y. M., Kang, Y., Gao, X., Xia, F., Xie, H., Sheu, L., Tsuk, S., Lotan, I., Tsushima, R. G., & Gaisano, H. Y. (2003) · Journal of Biological Chemistry

Ion channel regulation and functionCellular transport and secretion

Cited by 126

SNAREing Voltage-Gated K+ and ATP-Sensitive K+ Channels: Tuning β-Cell Excitability with Syntaxin-1A and Other Exocytotic Proteins

Leung, Y. M., Kwan, E. P., Ng, B., Kang, Y., & Gaisano, H. Y. (2007) · Endocrine Reviews

Pancreatic function and diabetesCellular transport and secretion

Cited by 106

Relative handgrip strength is inversely associated with metabolic profile and metabolic disease in the general population in China

Li, D., Guo, G., Xia, L., Yang, X., Zhang, B., Liu, F., Ma, J., Hu, Z., Li, Y., Li, W., et al. (2018) · Frontiers in Physiology

Diabetes, Cardiovascular Risks, and LipoproteinsPhysical Activity and Health

Cited by 101

SUMOylation Regulates Insulin Exocytosis Downstream of Secretory Granule Docking in Rodents and Humans

Dai, X.-Q., Plummer, G., Casimir, M., Kang, Y., Hajmrle, C., Gaisano, H. Y., Manning Fox, J. E., & MacDonald, P. E. (2011) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 92

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature

Low, J. T., Zavortink, M., Mitchell, J. M., Gan, W. J., Do, O. H., Schwiening, C. J., Gaisano, H. Y., & Thorn, P. (2014) · Diabetologia

Pancreatic function and diabetesCellular transport and secretion

Cited by 89

Dual Role of VAMP8 in Regulating Insulin Exocytosis and Islet β Cell Growth

Zhu, D., Zhang, Y., Lam, P. P. L., Dolai, S., Liu, Y., Cai, E. P., Choi, D., Schroer, S. A., Kang, Y., Allister, E. M., et al. (2012) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 87

Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells

Zhu, D., Koo, E., Kwan, E., Kang, Y., Park, S., Xie, H., Sugita, S., & Gaisano, H. Y. (2013) · Diabetologia

Pancreatic function and diabetesCellular transport and secretion

Cited by 81

Synaptosome-Associated Protein of 25 Kilodaltons Modulates Kv2.1 Voltage-Dependent K+ Channels in Neuroendocrine Islet β-Cells through an Interaction with the Channel N Terminus

MacDonald, P. E., Wang, G., Tsuk, S., Dodo, C., Kang, Y., Tang, L., Wheeler, M. B., Cattral, M. S., Lakey, J. R. T., Salapatek, A. M. F., et al. (2002) · Molecular Endocrinology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 78

Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counterregulation in Biobreeding Diabetic Rats

Karimian, N., Qin, T., Liang, T., Osundiji, M., Huang, Y., Teich, T., Riddell, M. C., Cattral, M. S., Coy, D. H., Vranic, M., et al. (2013) · Diabetes

Pancreatic function and diabetesDiabetes Management and Research

Cited by 66

Direct Interaction of Target SNAREs with the Kv2.1 Channel

Michaelevski, I., Chikvashvili, D., Tsuk, S., Singer-Lahat, D., Kang, Y., Linial, M., Gaisano, H. Y., Fili, O., & Lotan, I. (2003) · Journal of Biological Chemistry

Cellular transport and secretionIon channel regulation and function

Cited by 63

Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells

Dolai, S., Xie, L., Zhu, D., Liang, T., Qin, T., Xie, H., Kang, Y., Chapman, E. R., & Gaisano, H. Y. (2016) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 55

Characterization of Erg K+ Channels in α- and β-Cells of Mouse and Human Islets

Hardy, A. B., Fox, J. E. M., Giglou, P. R., Wijesekara, N., Bhattacharjee, A., Sultan, S., Gyulkhandanyan, A. V., Gaisano, H. Y., MacDonald, P. E., & Wheeler, M. B. (2009) · Journal of Biological Chemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 54

Here come the newcomer granules, better late than never

Gaisano, H. Y. (2014) · Trends in Endocrinology & Metabolism

Cellular transport and secretionPancreatic function and diabetes

Cited by 53

Munc18b Is a Major Mediator of Insulin Exocytosis in Rat Pancreatic β-Cells

Lam, P. P. L., Ohno, M., Dolai, S., He, Y., Qin, T., Liang, T., Zhu, D., Kang, Y., Liu, Y., Kauppi, M., et al. (2013) · Diabetes

Cellular transport and secretionPancreatic function and diabetes

Cited by 44

Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

Low, J. T., Mitchell, J. M., Do, O. H., Bax, J., Rawlings, A., Zavortink, M., Morgan, G., Parton, R. G., Gaisano, H. Y., & Thorn, P. (2013) · Diabetologia

Pancreatic function and diabetesCellular transport and secretion

Cited by 43

Activation of Exchange Protein Directly Activated by Cyclic Adenosine Monophosphate and Protein Kinase A Regulate Common and Distinct Steps in Promoting Plasma Membrane Exocytic and Granule-to-Granule Fusions in Rat Islet β Cells

Kwan, E. P., Gao, X., Leung, Y. M., & Gaisano, H. Y. (2007) · Pancreas

Pancreatic function and diabetesCellular transport and secretion

Cited by 33