Hiller, Sebastian

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Sborgi, L., Rühl, S., Mulvihill, E., Pipercevic, J., Heilig, R., Stahlberg, H., Farady, C. J., Müller, D. J., Broz, P., & Hiller, S. (2016) · The EMBO Journal

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 1,152

Solution structure of the integral human membrane protein VDAC-1 in detergent micelles

Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008) · Science

Protein Structure and DynamicsLipid Membrane Structure and Behavior

Cited by 667

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

Zhong, F. L., Mamaï, O., Sborgi, L., Boussofara, L., Hopkins, R., Robinson, K., Szeverényi, I., Takeichi, T., Balaji, R., Lau, A., et al. (2016) · Cell

Inflammasome and immune disordersGenetic and rare skin diseases.

Cited by 440

Regulation of α-synuclein by chaperones in mammalian cells

Burmann, B. M., Gerez, J. A., Matečko-Burmann, I., Campioni, S., Kumari, P., Ghosh, D., Mazur, A., Aspholm, E. E., Šulskis, D., Wawrzyniuk, M., et al. (2020) · Nature

Parkinson's Disease Mechanisms and TreatmentsHeat shock proteins research

Cited by 255

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

Suzuki, C., Garces, R. G., Edmonds, K. A., Hiller, S., Hyberts, S. G., Marintchev, A., & Wagner, G. (2008) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 165

Chaperone-Bound Clients: The Importance of Being Dynamic

Hiller, S. (2019) · Trends in Biochemical Sciences

Heat shock proteins researchProtein Structure and Dynamics

Cited by 54

Completing the BASEL phage collection to unlock hidden diversity for systematic exploration of phage–host interactions

Humolli, D., Piel, D., Maffei, E., Heyer, Y., Agustoni, E., Shaidullina, A., Willi, L., Imwinkelried, P., Estermann, F., Cuénod, A., et al. (2025) · PLOS Biology

Bacteriophages and microbial interactionsBacterial Genetics and Biotechnology

Cited by 36