Dinauer, Mary C.

Mouse model of x-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

Pollock, J. D., Williams, D. A., Gifford, M. A. C., Li, L. L., Du, X., Fisherman, J., Orkin, S. H., Doerschuk, C. M., & Dinauer, M. C. (1995) · Nature Genetics

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

Martyn, K. D., Frederick, L. M., von Loehneysen, K., Dinauer, M. C., & Knaus, U. G. (2006) · Cellular Signalling

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

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Activation of antibacterial autophagy by NADPH oxidases

Huang, J., Canadien, V., Lam, G. Y., Steinberg, B. E., Dinauer, M. C., Magalhaes, M. A. O., Glogauer, M., Grinstein, S., & Brumell, J. H. (2009) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyNeutrophil, Myeloperoxidase and Oxidative Mechanisms

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Deficiency of the Hematopoietic Cell-Specific Rho Family GTPase Rac2 Is Characterized by Abnormalities in Neutrophil Function and Host Defense

Roberts, A. W., Kim, C., Zhen, L., Lowe, J. B., Kapur, R., Petryniak, B., Spaetti, A., Pollock, J. D., Borneo, J. B., Bradford, G. B., et al. (1999) · Immunity

Neutrophil, Myeloperoxidase and Oxidative MechanismsProtein Kinase Regulation and GTPase Signaling

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The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex

Dinauer, M. C., Orkin, S. H., Brown, R., Jesaitis, A. J., & Parkos, C. A. (1987) · Nature

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

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Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus

Morgenstern, D. E., Gifford, M. A. C., Li, L. L., Doerschuk, C. M., & Dinauer, M. C. (1997) · The Journal of Experimental Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 370

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

Walder, C. E., Green, S. P., Darbonne, W. C., Mathias, J., Rae, J., Dinauer, M. C., Curnutte, J. T., & Thomas, G. R. (1997) · Stroke

Acute Ischemic Stroke ManagementNeuroprotection in Cerebral Ischemia

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Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease

Bustamante, J., Arias, A. A., Vogt, G., Picard, C., Galicia, L. B., Prando, C., Grant, A. V., Marchal, C. C., Hubeau, M., Chapgier, A., et al. (2011) · Nature Immunology

Immunodeficiency and Autoimmune DisordersTuberculosis Research and Epidemiology

Cited by 287

Gp91 phox is the heme binding subunit of the superoxide-generating NADPH oxidase

Yu, L., Quinn, M. T., Cross, A. R., & Dinauer, M. C. (1998) · Proceedings of the National Academy of Sciences

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

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Impaired Superoxide Production Due to a Deficiency in Phagocyte NADPH Oxidase Fails to Inhibit Atherosclerosis in Mice

Kirk, E. A., Dinauer, M. C., Rosen, H., Chait, A., Heinecke, J. W., & LeBoeuf, R. C. (2000) · Arteriosclerosis, Thrombosis, and Vascular Biology

Nitric Oxide and Endothelin EffectsAtherosclerosis and Cardiovascular Diseases

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Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

Wiemann, P., Perevitsky, A., Lim, F. Y., Shadkchan, Y., Knox, B. P., Landero Figueora, J. A., Choera, T., Niu, M., Steinberger, A. J., Wüthrich, M., et al. (2017) · Cell Reports

Antifungal resistance and susceptibilityFungal and yeast genetics research

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Impaired Phagocytosis of Apoptotic Cells by Macrophages in Chronic Granulomatous Disease Is Reversed by IFN-γ in a Nitric Oxide-Dependent Manner

Fernandez-Boyanapalli, R., McPhillips, K. A., Frasch, S. C., Janssen, W. J., Dinauer, M. C., Riches, D. W. H., Henson, P. M., Byrne, A., & Bratton, D. L. (2010) · The Journal of Immunology

Phagocytosis and Immune RegulationNeutrophil, Myeloperoxidase and Oxidative Mechanisms

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