Ottoboni, Linda

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

International MS Genetics Consortium, De Jager, P. L., Jia, X., Wang, J., de Bakker, P. I. W., Ottoboni, L., Aggarwal, N. T., Piccio, L., Raychaudhuri, S., Tran, D., et al. (2009) · Nature Genetics

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 800

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

Initiative, T. A. D. N., Bradshaw, E. M., Chibnik, L. B., Keenan, B. T., Ottoboni, L., Raj, T., Tang, A., Rosenkrantz, L. L., Imboywa, S., Lee, M., et al. (2013) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 570

Convergence between microglia and peripheral macrophages phenotype during development and neuroinflammation

Grassivaro, F., Menon, R., Acquaviva, M., Ottoboni, L., Ruffini, F., Bergamaschi, A., Muzio, L., Farina, C., & Martino, G. (2020) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 127

Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis

Starost, L., Lindner, M., Herold, M., Xu, Y. K. T., Drexler, H. C. A., Heß, K., Ehrlich, M., Ottoboni, L., Ruffini, F., Stehling, M., et al. (2020) · Acta Neuropathologica

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 79

Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration

Colombo, E., Bassani, C., De Angelis, A., Ruffini, F., Ottoboni, L., Comi, G., Martino, G., & Farina, C. (2020) · Frontiers in Immunology

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 66

Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis

Muzio, L., Sirtori, R., Gornati, D., Eleuteri, S., Fossaghi, A., Brancaccio, D., Manzoni, L., Ottoboni, L., Feo, L. D., Quattrini, A., et al. (2020) · Nature Communications

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 65

Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo

Mozafari, S., Starost, L., Manot-Saillet, B., Garcia-Diaz, B., Xu, Y. K. T., Roussel, D., Levy, M. J. F., Ottoboni, L., Kim, K.-P., Schöler, H. R., et al. (2020) · Science Advances

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

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One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2

Chanoumidou, K., Hernández-Rodríguez, B., Windener, F., Thomas, C., Stehling, M., Mozafari, S., Albrecht, S., Ottoboni, L., Antel, J., Kim, K.-P., et al. (2021) · Stem Cell Reports

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

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