Hattersley, Andrew T.

Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects

Ellard, S., Flanagan, S. E., Girard, C. A., Patch, A.-M., Harries, L. W., Parrish, A., Edghill, E. L., Mackay, D. J. G., Proks, P., Shimomura, K., et al. (2007) · The American Journal of Human Genetics

Pancreatic function and diabetesIon channel regulation and function

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Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting

Wright, C. F., West, B., Tuke, M., Jones, S. E., Patel, K., Laver, T. W., Beaumont, R. N., Tyrrell, J., Wood, A. R., Frayling, T. M., et al. (2019) · The American Journal of Human Genetics

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 212

Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis

Garin, I., Edghill, E. L., Akerman, I., Rubio-Cabezas, O., Rica, I., Locke, J. M., Maestro, M. A., Alshaikh, A., Bundak, R., del Castillo, G., et al. (2010) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 211

ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of monogenic diabetes in children and adolescents

Greeley, S. A. W., Polak, M., Njølstad, P. R., Barbetti, F., Williams, R., Castano, L., Raile, K., Chi, D. V., Habeb, A., Hattersley, A. T., et al. (2022) · Pediatric Diabetes

Diabetes and associated disordersPancreatic function and diabetes

Cited by 211

Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

Chung, W. K., Erion, K., Florez, J. C., Hattersley, A. T., Hivert, M.-F., Lee, C. G., McCarthy, M. I., Nolan, J. J., Norris, J. M., Pearson, E. R., et al. (2020) · Diabetologia

Diabetes Management and ResearchDiabetes and associated disorders

Cited by 203

The diagnosis and management of monogenic diabetes in children and adolescents

Rubio-Cabezas, O., Hattersley, A. T., Njølstad, P. R., Mlynarski, W., Ellard, S., White, N., Chi, D. V., & Craig, M. E. (2014) · Pediatric Diabetes

Diabetes and associated disordersPancreatic function and diabetes

Cited by 196

Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes

Thomas, N. J., Lynam, A. L., Hill, A. V., Weedon, M. N., Shields, B. M., Oram, R. A., McDonald, T. J., Hattersley, A. T., & Jones, A. G. (2019) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 183

A Common Variation in Deiodinase 1 Gene DIO1 Is Associated with the Relative Levels of Free Thyroxine and Triiodothyronine

Panicker, V., Cluett, C., Shields, B., Murray, A., Parnell, K. S., Perry, J. R. B., Weedon, M. N., Singleton, A., Hernandez, D., Evans, J., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 155

Population-based assessment of a biomarker-based screening pathway to aid diagnosis of monogenic diabetes in young-onset patients

Shields, B. M., Shepherd, M., Hudson, M., McDonald, T. J., Colclough, K., Peters, J., Knight, B., Hyde, C., Ellard, S., Pearson, E. R., et al. (2017) · Diabetes Care

Diabetes and associated disordersPancreatic function and diabetes

Cited by 151

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: a prospective study in children

Bonifacio, E., Beyerlein, A., Hippich, M., Winkler, C., Vehik, K., Weedon, M. N., Laimighofer, M., Hattersley, A. T., Krumsiek, J., Frohnert, B. I., et al. (2018) · PLOS Medicine

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 148

Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors

Oram, R. A., McDonald, T. J., Shields, B. M., Hudson, M. M., Shepherd, M. H., Hammersley, S., Pearson, E. R., Hattersley, A. T., & on behalf of the UNITED Team (2015) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 133

Increased all-cause and cardiovascular mortality in monogenic diabetes as a result of mutations in the HNF1A gene

Steele, A. M., Shields, B. M., Shepherd, M., Ellard, S., Hattersley, A. T., & Pearson, E. R. (2010) · Diabetic Medicine

Diabetes and associated disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 130

Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature

Shields, B. M., Peters, J. L., Cooper, C., Lowe, J., Knight, B. A., Powell, R. J., Jones, A., Hyde, C. J., & Hattersley, A. T. (2015) · BMJ Open

Diabetes and associated disordersDiabetes Management and Research

Cited by 126

Hypoglycaemic counter-regulation at normal blood glucose concentrations in patients with well controlled type-2 diabetes

Spyer, G., Hattersley, A. T., MacDonald, I., Amiel, S., & MacLeod, K. M. (2000) · The Lancet

Diabetes Management and ResearchDiabetes Treatment and Management

Cited by 126

Latent autoimmune diabetes of adults (LADA) is likely to represent a mixed population of autoimmune (type 1) and nonautoimmune (type 2) diabetes

Jones, A. G., McDonald, T. J., Shields, B. M., Hagopian, W., & Hattersley, A. T. (2021) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 122

A method of identifying and correcting miscoding, misclassification and misdiagnosis in diabetes: a pilot and validation study of routinely collected data

De Lusignan, S., Khunti, K., Belsey, J., Hattersley, A., Van Vlymen, J., Gallagher, H., Millett, C., Hague, N. J., Tomson, C., Harris, K., et al. (2010) · Diabetic Medicine

Medical Coding and Health InformationElectronic Health Records Systems

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Monogenic Diabetes: From Genetic Insights to Population-Based Precision in Care. Reflections From a Diabetes Care Editors’ Expert Forum

Riddle, M. C., Philipson, L. H., Rich, S. S., Carlsson, A., Franks, P. W., Greeley, S. A. W., Nolan, J. J., Pearson, E. R., Zeitler, P. S., & Hattersley, A. T. (2020) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 117

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., et al. (2023) · Nature Biotechnology

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 111

Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should lead to testing for MODY: lessons from a 5-year pediatric Swedish National Cohort Study

Carlsson, A., Shepherd, M., Ellard, S., Weedon, M., Lernmark, Å., Forsander, G., Colclough, K., Brahimi, Q., Valtonen-Andre, C., Ivarsson, S. A., et al. (2020) · Diabetes Care

Diabetes and associated disordersPancreatic function and diabetes

Cited by 111

Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young

Gloyn, A. L., Odili, S., Zelent, D., Buettger, C., Castleden, H. A. J., Steele, A. M., Stride, A., Shiota, C., Magnuson, M. A., Lorini, R., et al. (2005) · Journal of Biological Chemistry

Pancreatic function and diabetesGlycogen Storage Diseases and Myoclonus

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High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes

McDonald, T. J., Shields, B. M., Lawry, J., Owen, K. R., Gloyn, A. L., Ellard, S., & Hattersley, A. T. (2011) · Diabetes Care

Diabetes and associated disordersPancreatic function and diabetes

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Predicting and elucidating the etiology of fatty liver disease: a machine learning modeling and validation study in the IMI DIRECT cohorts

Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., et al. (2020) · PLOS Medicine

Liver Disease Diagnosis and TreatmentAlcohol Consumption and Health Effects

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Lessons From the Mixed-Meal Tolerance Test

Besser, R. E. J., Shields, B. M., Casas, R., Hattersley, A. T., & Ludvigsson, J. (2013) · Diabetes Care

Diabetes Management and ResearchDiabetes and associated disorders

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Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes

Babiker, T., Vedovato, N., Patel, K., Thomas, N., Finn, R., Männikkö, R., Chakera, A. J., Flanagan, S. E., Shepherd, M. H., Ellard, S., et al. (2016) · Diabetologia

Pancreatic function and diabetesIon channel regulation and function

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