High, Katherine A.

Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses

Hauck, B., Murphy, S. L., Smith, P. H., Qu, G., Liu, X., Zelenaia, O., Mingozzi, F., Sommer, J. M., High, K. A., & Wright, J. F. (2009) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 88

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

Hui, D. J., Edmonson, S. C., Podsakoff, G. M., Pien, G. C., Ivanciu, L., Camire, R. M., Ertl, H., Mingozzi, F., High, K. A., & Basner-Tschakarjan, E. (2015) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 84

Capsid-specific T-cell Responses to Natural Infections With Adeno-associated Viruses in Humans Differ From Those of Nonhuman Primates

Li, H., Lasaro, M. O., Jia, B., Lin, S. W., Haut, L. H., High, K. A., & Ertl, H. C. (2011) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 83

The Effect of CpG Sequences on Capsid-Specific CD8+ T Cell Responses to AAV Vector Gene Transfer

Xiang, Z., Kurupati, R. K., Li, Y., Kuranda, K., Zhou, X., Mingozzi, F., High, K. A., & Ertl, H. C. J. (2020) · Molecular Therapy

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 67

Self-complementary AAVs Induce More Potent Transgene Product-specific Immune Responses Compared to a Single-stranded Genome

Wu, T., Töpfer, K., Lin, S.-W., Li, H., Bian, A., Zhou, X. Y., High, K. A., & Ertl, H. C. (2012) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 66

A Phase 1/2 Trial of Investigational Spk-8011 in Hemophilia a Demonstrates Durable Expression and Prevention of Bleeds

High, K. A., George, L. A., Eyster, M. E., Sullivan, S. K., Ragni, M. V., Croteau, S. E., Samelson-Jones, B. J., Evans, M., Joseney-Antoine, M., Macdougall, A., et al. (2018) · Blood

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 57

CD8+ T cell recognition of epitopes within the capsid of adeno-associated virus 8-based gene transfer vectors depends on vectors' genome

Wu, T.-L., Li, H., Faust, S. M., Chi, E., Zhou, S., Wright, F., High, K. A., & Ertl, H. C. (2014) · Molecular Therapy

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 38

Effects of immunosuppression on circulating adeno-associated virus capsid-specific T cells in humans

Parzych, E. M., Li, H., Yin, X., Liu, Q., Wu, T.-L., Podsakoff, G. M., High, K. A., Levine, M. H., & Ertl, H. C. J. (2013) · Human Gene Therapy

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 16