Mastaitis, Jason

Activin A more prominently regulates muscle mass in primates than does GDF8

Latres, E., Mastaitis, J., Fury, W., Miloscio, L., Trejos, J., Pangilinan, J., Okamoto, H., Cavino, K., Na, E., Papatheodorou, A., et al. (2017) · Nature Communications

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 185

Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice

Latres, E., Pangilinan, J., Miloscio, L., Bauerlein, R., Na, E., Potocky, T. B., Huang, Y., Eckersdorff, M., Rafique, A., Mastaitis, J., et al. (2015) · Skeletal Muscle

Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research

Cited by 143

GDF8 and activin A blockade protects against GLP-1–induced muscle loss while enhancing fat loss in obese male mice and non-human primates

Mastaitis, J. W., Gomez, D., Raya, J. G., Li, D., Min, S., Stec, M., Kleiner, S., McWilliams, T., Altarejos, J. Y., Murphy, A. J., et al. (2025) · Nature Communications

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 53

Activin E–ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice

Adam, R. C., Pryce, D. S., Lee, J. S., Zhao, Y., Mintah, I. J., Min, S., Halasz, G., Mastaitis, J., Atwal, G. S., Aykul, S., et al. (2023) · Proceedings of the National Academy of Sciences

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 44

GDF8 and activin A are the key negative regulators of muscle mass in postmenopausal females: a randomized phase I trial

Gonzalez Trotter, D., Donahue, S., Wynne, C., Ali, S., Parasoglou, P., Boyapati, A., Mohammadi, K., Musser, B. J., Meier, P., Mastaitis, J., et al. (2025) · Nature Communications

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 23

207-OR: Myostatin Inhibition Synergizes with GLP-1R Agonism to Accelerate Weight Loss in Male, Obese Nonhuman Primates

MASTAITIS, J., GOMEZ, D., LE ROUZIC, V., STEC, M., KHAN, N., NA, E., MCWILLIAMS, T., MIN, S., & SLEEMAN, M. (2023) · Diabetes

Muscle Physiology and DisordersPharmacology and Obesity Treatment

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