Adjali, Oumeya

Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy

Le Guiner, C., Servais, L., Montus, M., Larcher, T., Fraysse, B., Moullec, S., Allais, M., François, V., Dutilleul, M., Malerba, A., et al. (2017) · Nature Communications

Virus-based gene therapy researchMuscle Physiology and Disorders

Cited by 246

Unraveling the complex story of immune responses to AAV vectors trial after trial.

Vandamme, C., Adjali, O., & Mingozzi, F. (2017) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 234

Safety and long-term efficacy of AAV4 gene therapy in patients with RPE65 leber congenital amaurosis

Le Meur, G., Lebranchu, P., Billaud, F., Adjali, O., Schmitt, S., Bézieau, S., Péréon, Y., Valabregue, R., Ivan, C., Darmon, C., et al. (2018) · Molecular Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 137

Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells

Ferrari, S., Jacob, A., Cesana, D., Laugel, M., Beretta, S., Varesi, A., Unali, G., Conti, A., Canarutto, D., Albano, L., et al. (2022) · Cell stem cell

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 133

Chemical modification of the adeno-associated virus capsid to improve gene delivery

Mével, M., Bouzelha, M., Leray, A., Pacouret, S., Guilbaud, M., Penaud-Budloo, M., Alvarez-Dorta, D., Dubreil, L., Gouin, S. G., Combal, J. P., et al. (2020) · Chemical Science

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 92

Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity

Tran, N. T., Lecomte, E., Saleun, S., Namkung, S., Robin, C., Weber, K., Devine, E., Blouin, V., Adjali, O., Ayuso, E., et al. (2022) · Human Gene Therapy

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 74

Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls

François, A., Bouzelha, M., Lecomte, E., Broucque, F., Penaud-Budloo, M., Adjali, O., Moullier, P., Blouin, V., & Ayuso, E. (2018) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 50

Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation

Vandamme, C., Xicluna, R., Hesnard, L., Devaux, M., Jaulin, N., Guilbaud, M., Le Duff, J., Couzinié, C., Moullier, P., Saulquin, X., et al. (2020) · Frontiers in Immunology

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 23

Risk mitigation of immunogenicity: a key to personalized retinal gene therapy

Varin, J., Morival, C., Maillard, N., Adjali, O., & Cronin, T. (2021) · International Journal of Molecular Sciences

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 19

Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina

Leray, A., Lalys, P.-A., Varin, J., Bouzelha, M., Bourdon, A., Alvarez-Dorta, D., Pavageau, K., Depienne, S., Marchand, M., Mellet, A., et al. (2024) · Biomedicine & Pharmacotherapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 17

Stability of the adeno-associated virus 8 reference standard material

Penaud-Budloo, M., Broucque, F., Harrouet, K., Bouzelha, M., Saleun, S., Douthe, S., D’Costa, S., Ogram, S., Adjali, O., Blouin, V., et al. (2019) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 14