Reinheckel, Thomas

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J., & Golenbock, D. T. (2008) · Nature Immunology

Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 2,441

Comparative resistance of the 20S and 26S proteasome to oxidative stress

REINHECKEL, T., SITTE, N., ULLRICH, O., KUCKELKORN, U., DAVIES, K. J. A., & GRUNE, T. (1998) · Biochemical Journal

Ubiquitin and proteasome pathwaysRedox biology and oxidative stress

Cited by 447

“Thyroid functions of mouse cathepsins b, K and l

Friedrichs, B., Tepel, C., Reinheckel, T., Deussing, J., von Figura, K., Herzog, V., Peters, C., Saftig, P., & Brix, K. (2003) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsProtease and Inhibitor Mechanisms

Cited by 226

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

Oberle, C., Huai, J., Reinheckel, T., Tacke, M., Rassner, M., Ekert, P. G., Buellesbach, J., & Borner, C. (2010) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 193

CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients

Fløyel, T., Brorsson, C., Nielsen, L. B., Miani, M., Bang-Berthelsen, C. H., Friedrichsen, M., Overgaard, A. J., Berchtold, L. A., Wiberg, A., Poulsen, P., et al. (2014) · Proceedings of the National Academy of Sciences

Diabetes and associated disordersPancreatic function and diabetes

Cited by 104

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

Sevenich, L., Werner, F., Gajda, M., Schurigt, U., Sieber, C., Müller, S., Follo, M., Peters, C., & Reinheckel, T. (2011) · Oncogene

Protease and Inhibitor MechanismsAngiogenesis and VEGF in Cancer

Cited by 85

BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation

Reischmann, N., Andrieux, G., Griffin, R., Reinheckel, T., Boerries, M., & Brummer, T. (2020) · Oncogene

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

Cited by 37