Kieffer, Yann

Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer

Costa, A., Kieffer, Y., Scholer-Dahirel, A., Pelon, F., Bourachot, B., Cardon, M., Sirven, P., Magagna, I., Fuhrmann, L., Bernard, C., et al. (2018) · Cancer Cell

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 1,705

Single-cell analysis reveals fibroblast clusters linked to immunotherapy resistance in cancer.

Kieffer, Y., Hocine, H. R., Gentric, G., Pelon, F., Bernard, C., Bourachot, B., Lameiras, S., Albergante, L., Bonneau, C., Guyard, A., et al. (2020) · Cancer Discovery

Cancer Immunotherapy and BiomarkersSingle-cell and spatial transcriptomics

Cited by 910

miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers

Givel, A.-M., Kieffer, Y., Scholer-Dahirel, A., Sirven, P., Cardon, M., Pelon, F., Magagna, I., Gentric, G., Costa, A., Bonneau, C., et al. (2018) · Nature Communications

Ovarian cancer diagnosis and treatmentChemokine receptors and signaling

Cited by 295

Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients

Gruosso, T., Mieulet, V., Cardon, M., Bourachot, B., Kieffer, Y., Devun, F., Dubois, T., Dutreix, M., Vincent‐Salomon, A., Miller, K. M., et al. (2016) · EMBO Molecular Medicine

DNA Repair MechanismsGenomics, phytochemicals, and oxidative stress

Cited by 179

Stiffness Increases with Myofibroblast Content and Collagen Density in Mesenchymal High Grade Serous Ovarian Cancer

Mieulet, V., Garnier, C., Kieffer, Y., Guilbert, T., Nemati, F., Marangoni, E., Renault, G., Chamming’s, F., Vincent-Salomon, A., & Mechta-Grigoriou, F. (2021) · Scientific Reports

Cellular Mechanics and InteractionsOvarian cancer diagnosis and treatment

Cited by 79