Horwitz, Marcus A.

Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes

Horwitz, M. A., & Silverstein, S. C. (1980) · Journal of Clinical Investigation

Legionella and Acanthamoeba researchMicrobial infections and disease research

Cited by 639

Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron.

Byrd, T. F., & Horwitz, M. A. (1989) · Journal of Clinical Investigation

Legionella and Acanthamoeba researchIron Metabolism and Disorders

Cited by 320

Targeted Intracellular Delivery of Antituberculosis Drugs to Mycobacterium tuberculosis-Infected Macrophages via Functionalized Mesoporous Silica Nanoparticles

Clemens, D. L., Lee, B.-Y., Xue, M., Thomas, C. R., Meng, H., Ferris, D., Nel, A. E., Zink, J. I., & Horwitz, M. A. (2012) · Antimicrobial Agents and Chemotherapy

Nanoparticle-Based Drug DeliveryTuberculosis Research and Epidemiology

Cited by 260

Discovery and characterization of a unique mycobacterial heme acquisition system

Tullius, M. V., Harmston, C. A., Owens, C. P., Chim, N., Morse, R. P., McMath, L. M., Iniguez, A., Kimmey, J. M., Sawaya, M. R., Whitelegge, J. P., et al. (2011) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyIron Metabolism and Disorders

Cited by 199

Thiol Antioxidants Inhibit the Adjuvant Effects of Aerosolized Diesel Exhaust Particles in a Murine Model for Ovalbumin Sensitization

Whitekus, M. J., Li, N., Zhang, M., Wang, M., Horwitz, M. A., Nelson, S. K., Horwitz, L. D., Brechun, N., Diaz-Sanchez, D., & Nel, A. E. (2002) · The Journal of Immunology

Air Quality and Health ImpactsAsthma and respiratory diseases

Cited by 198

Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma.

Byrd, T. F., & Horwitz, M. A. (1993) · Journal of Clinical Investigation

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 149

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron

Stefanova, D., Raychev, A., Arezes, J., Ruchala, P., Gabayan, V., Skurnik, M., Dillon, B. J., Horwitz, M. A., Ganz, T., Bulut, Y., et al. (2017) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 145

Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens.

Byrd, T. F., & Horwitz, M. A. (1991) · Journal of Clinical Investigation

Legionella and Acanthamoeba researchBacterial biofilms and quorum sensing

Cited by 120