Contrepois, Kévin

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

Garrett-Bakelman, F. E., Darshi, M., Green, S. J., Gur, R. C., Lin, L., Macias, B. R., McKenna, M. J., Meydan, C., Mishra, T., Nasrini, J., et al. (2019) · Science

Spaceflight effects on biologySpace exploration and regulation

Cited by 1,128

Longitudinal multi-omics of host–microbe dynamics in prediabetes

Zhou, W., Sailani, M. R., Contrepois, K., Zhou, Y., Ahadi, S., Leopold, S. R., Zhang, M. J., Rao, V., Avina, M., Mishra, T., et al. (2019) · Nature

Adipokines, Inflammation, and Metabolic DiseasesGut microbiota and health

Cited by 583

Molecular Choreography of Acute Exercise

Contrepois, K., Wu, S., Moneghetti, K. J., Hornburg, D., Ahadi, S., Tsai, M.-S., Metwally, A. A., Wei, E., Lee-McMullen, B., Quijada, J. V., et al. (2020) · Cell

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 502

A Longitudinal Big Data Approach for Precision Health

Schüssler-Fiorenza Rose, S. M., Contrepois, K., Moneghetti, K. J., Zhou, W., Mishra, T., Mataraso, S., Dagan-Rosenfeld, O., Ganz, A. B., Dunn, J., Hornburg, D., et al. (2019) · Nature Medicine

Health, Environment, Cognitive AgingMetabolomics and Mass Spectrometry Studies

Cited by 494

Physiological blood–brain transport is impaired with age by a shift in transcytosis

Yang, A. C., Stevens, M. Y., Chen, M. B., Lee, D. P., Stähli, D., Gate, D., Contrepois, K., Chen, W., Iram, T., Zhang, L., et al. (2020) · Nature

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 477

Exercise plasma boosts memory and dampens brain inflammation via clusterin

De Miguel, Z., Khoury, N., Betley, M. J., Lehallier, B., Willoughby, D., Olsson, N., Yang, A. C., Hahn, O., Lu, N., Vest, R. T., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsClusterin in disease pathology

Cited by 422

Personal aging markers and ageotypes revealed by deep longitudinal profiling

Ahadi, S., Zhou, W., Schüssler-Fiorenza Rose, S. M., Sailani, M. R., Contrepois, K., Avina, M., Ashland, M., Brunet, A., & Snyder, M. (2020) · Nature Medicine

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 408

An exercise-inducible metabolite that suppresses feeding and obesity

Li, V. L., He, Y., Contrepois, K., Liu, H., Kim, J. T., Wiggenhorn, A. L., Tanzo, J. T., Tung, A. S.-H., Lyu, X., Zushin, P.-J. H., et al. (2022) · Nature

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 331

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

Contrepois, K., Coudereau, C., Benayoun, B. A., Schuler, N., Roux, P.-F., Bischof, O., Courbeyrette, R., Carvalho, C., Thuret, J.-Y., Ma, Z., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 191