Hallam, Dean

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure

Hallam, D., Collin, J., Bojic, S., Chichagova, V., Buskin, A., Xu, Y., Lafage, L., Otten, E. G., Anyfantis, G., Mellough, C., et al. (2017) · Stem Cells

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 75

Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids

Dorgau, B., Felemban, M., Hilgen, G., Kiening, M., Zerti, D., Hunt, N. C., Doherty, M., Whitfield, P., Hallam, D., White, K., et al. (2019) · Biomaterials

Retinal Development and DisordersTissue Engineering and Regenerative Medicine

Cited by 69

Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

Cerniauskas, E., Kurzawa-Akanbi, M., Xie, L., Hallam, D., Moya-Molina, M., White, K., Steel, D., Doherty, M., Whitfield, P., Al-Aama, J., et al. (2020) · Stem Cells Translational Medicine

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 58

Revisiting the role of factor H in age-related macular degeneration: Insights from complement-mediated renal disease and rare genetic variants

Tzoumas, N., Hallam, D., Harris, C. L., Lako, M., Kavanagh, D., & Steel, D. H. W. (2021) · Survey of Ophthalmology

Complement system in diseasesRetinal Diseases and Treatments

Cited by 33