Williams, Dominic

Reproducing human and cross-species drug toxicities using a liver-chip

Jang, K.-J., Otieno, M. A., Ronxhi, J., Lim, H.-K., Ewart, L., Kodella, K. R., Petropolis, D. B., Kulkarni, G., Rubins, J. E., Conegliano, D., et al. (2019) · Science Translational Medicine

Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research

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Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

Proctor, W. R., Foster, A. J., Vogt, J., Summers, C., Middleton, B., Pilling, M. A., Shienson, D., Kijanska, M., Ströbel, S., Kelm, J. M., et al. (2017) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 328

Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Bell, C. C., Dankers, A. C. A., Lauschke, V. M., Sison-Young, R., Jenkins, R., Rowe, C., Goldring, C. E., Park, K., Regan, S. L., Walker, T., et al. (2018) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 327

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

Antoine, D. J., Williams, D. P., Kipar, A., Jenkins, R. E., Regan, S. L., Sathish, J. G., Kitteringham, N. R., & Park, B. K. (2009) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionCell death mechanisms and regulation

Cited by 223

Predicting Drug-Induced Liver Injury with Bayesian Machine Learning

Williams, D. P., Lazic, S. E., Foster, A. J., Semenova, E., & Morgan, P. (2020) · Chemical Research in Toxicology

Drug-Induced Hepatotoxicity and ProtectionComputational Drug Discovery Methods

Cited by 124

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid

Foster, A. J., Chouhan, B., Regan, S. L., Rollison, H., Amberntsson, S., Andersson, L. C., Srivastava, A., Darnell, M., Cairns, J., Lazic, S. E., et al. (2019) · Archives of Toxicology

Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research

Cited by 117