Aldape, Kenneth

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

Ji, H., Wang, J., Nika, H., Hawke, D., Keezer, S., Ge, Q., Fang, B., Fang, X., Fang, D., Litchfield, D. W., et al. (2009) · Molecular Cell

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

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Big data in basic and translational cancer research

Jiang, P., Sinha, S., Aldape, K., Hannenhalli, S., Sahinalp, C., & Ruppin, E. (2022) · Nature Reviews Cancer

Cancer Genomics and DiagnosticsBioinformatics and Genomic Networks

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Comprehensive Genomic Analysis in NRG Oncology/RTOG 9802: A Phase III Trial of Radiation Versus Radiation Plus Procarbazine, Lomustine (CCNU), and Vincristine in High-Risk Low-Grade Glioma

Bell, E. H., Zhang, P., Shaw, E. G., Buckner, J. C., Barger, G. R., Bullard, D. E., Mehta, M. P., Gilbert, M. R., Brown, P. D., Stelzer, K. J., et al. (2020) · Journal of Clinical Oncology

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

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Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks

Chen, J. C., Alvarez, M. J., Talos, F., Dhruv, H., Rieckhof, G. E., Iyer, A., Diefes, K. L., Aldape, K., Berens, M., Shen, M. M., et al. (2014) · Cell

Bioinformatics and Genomic NetworksGlioma Diagnosis and Treatment

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A deep-learning framework to predict cancer treatment response from histopathology images through imputed transcriptomics

Hoang, D.-T., Dinstag, G., Shulman, E. D., Hermida, L. C., Ben-Zvi, D. S., Elis, E., Caley, K., Sammut, S.-J., Sinha, S., Sinha, N., et al. (2024) · Nature Cancer

AI in cancer detectionRadiomics and Machine Learning in Medical Imaging

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CODEL: Phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design

Jaeckle, K. A., Ballman, K. V., van den Bent, M., Giannini, C., Galanis, E., Brown, P. D., Jenkins, R. B., Cairncross, J. G., Wick, W., Weller, M., et al. (2021) · Neuro-Oncology

Glioma Diagnosis and TreatmentPARP inhibition in cancer therapy

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A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas

Agnihotri, S., Wolf, A., Munoz, D. M., Smith, C. J., Gajadhar, A., Restrepo, A., Clarke, I. D., Fuller, G. N., Kesari, S., Dirks, P. B., et al. (2011) · Journal of Experimental Medicine

Glioma Diagnosis and TreatmentCancer-related Molecular Pathways

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The biological significance of tumor grade, age, enhancement, and extent of resection in IDH-mutant gliomas: How should they inform treatment decisions in the era of IDH inhibitors?

van den Bent, M. J., French, P. J., Brat, D., Tonn, J. C., Touat, M., Ellingson, B. M., Young, R. J., Pallud, J., von Deimling, A., Sahm, F., et al. (2024) · Neuro-Oncology

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

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RTOG 0825: Phase III double-blind placebo-controlled trial evaluating bevacizumab (Bev) in patients (Pts) with newly diagnosed glioblastoma (GBM).

Gilbert, M. R., Dignam, J., Won, M., Blumenthal, D. T., Vogelbaum, M. A., Aldape, K. D., Colman, H., Chakravarti, A., Jeraj, R., Armstrong, T. S., et al. (2013) · Journal of Clinical Oncology

Glioma Diagnosis and TreatmentAngiogenesis and VEGF in Cancer

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DNA methylation-based prognostic subtypes of chordoma tumors in tissue and plasma

Zuccato, J. A., Patil, V., Mansouri, S., Liu, J. C., Nassiri, F., Mamatjan, Y., Chakravarthy, A., Karimi, S., Almeida, J. P., Bernat, A.-L., et al. (2022) · Neuro-Oncology

Bone Tumor Diagnosis and TreatmentsHead and Neck Surgical Oncology

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