Mailand, Niels

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Falck, J., Mailand, N., Syljuåsen, R. G., Bartek, J., & Lukas, J. (2001) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 1,085

ATR prohibits replication catastrophe by preventing global exhaustion of RPA

Toledo, L. I., Altmeyer, M., Rask, M.-B., Lukas, C., Larsen, D. H., Povlsen, L. K., Bekker-Jensen, S., Mailand, N., Bartek, J., & Lukas, J. (2013) · Cell

DNA Repair MechanismsTelomeres, Telomerase, and Senescence

Cited by 911

Rapid Destruction of Human Cdc25A in Response to DNA Damage

Mailand, N., Falck, J., Lukas, C., Syljuåsen, R. G., Welcker, M., Bartek, J., & Lukas, J. (2000) · Science

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 787

Assembly and function of DNA double-strand break repair foci in mammalian cells

Bekker-Jensen, S., & Mailand, N. (2010) · DNA Repair

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 338

Regulation of G2/M events by Cdc25A through phosphorylation‐dependent modulation of its stability

Mailand, N., Podtelejnikov, A. V., Groth, A., Mann, M., Bartek, J., & Lukas, J. (2002) · The EMBO Journal

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 315

Destruction of Claspin by SCFβTrCP Restrains Chk1 Activation and Facilitates Recovery from Genotoxic Stress

Mailand, N., Bekker-Jensen, S., Bartek, J., & Lukas, J. (2006) · Molecular Cell

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 258

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Marteijn, J. A., Bekker-Jensen, S., Mailand, N., Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, J., & Vermeulen, W. (2009) · Journal of Cell Biology

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 184

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks.

Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, S., & Mailand, N. (2012) · Journal of Cell Biology

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 146

USP7 counteracts SCFβTrCP- but not APCCdh1-mediated proteolysis of Claspin

Faustrup, H., Bekker-Jensen, S., Bartek, J., Lukas, J., & Mailand, N. (2009) · The Journal of Cell Biology

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 113

Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage

Gibbs-Seymour, I., Markiewicz, E., Bekker-Jensen, S., Mailand, N., & Hutchison, C. J. (2015) · Aging Cell

Nuclear Structure and FunctionDNA Repair Mechanisms

Cited by 90

Structural basis of BRCC36 function in DNA repair and immune regulation

Rabl, J., Bunker, R. D., Schenk, A. D., Cavadini, S., Gill, M. E., Abdulrahman, W., Andrés-Pons, A., Luijsterburg, M. S., Ibrahim, A. F. M., Branigan, E., et al. (2019) · Molecular Cell

Ubiquitin and proteasome pathwaysDNA Repair Mechanisms

Cited by 84

Chemogenetic profiling reveals PP2A‐independent cytotoxicity of proposed PP2A activators iHAP1 and DT‐061

Vit, G., Duro, J., Rajendraprasad, G., Hertz, E. P. T., Holland, L. K. K., Weisser, M. B., McEwan, B. C., Lopez‐Mendez, B., Sotelo‐Parrilla, P., Jeyaprakash, A. A., et al. (2022) · The EMBO Journal

Protein Tyrosine PhosphatasesPI3K/AKT/mTOR signaling in cancer

Cited by 34

Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting

Vit, G., Duro, J., Rajendraprasad, G., Hertz, E. P. T., Kauffeldt Holland, L. K., Weisser, M. B., McEwan, B. C., Lopez-Mendez, B., Montoya, G., Mailand, N., et al. (2021) · The EMBO Journal

Protein Tyrosine PhosphatasesPI3K/AKT/mTOR signaling in cancer

Cited by 33