Kamadurai, Hari B.

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes

Zhang, W., Wu, K.-P., Sartori, M. A., Kamadurai, H. B., Ordureau, A., Jiang, C., Mercredi, P. Y., Murchie, R., Hu, J., Persaud, A., et al. (2016) · Molecular Cell

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

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Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

Kamadurai, H. B., Qiu, Y., Deng, A., Harrison, J. S., MacDonald, C., Actis, M., Rodrigues, P., Miller, D. J., Souphron, J., Lewis, S. M., et al. (2013) · eLife

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

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Abstract 5789: Discovery of a selective molecular glue degrader of CCNE1 for the treatment of CCNE1-amplified solid tumors and CDK4/6i-resistant HR+/HER2- breast cancers

Vincent, B. M., Marcoux, D., Caligioni, C., Bart, A. G., Harlow, M. L., Hsu, R. Y., Singh, P., Badger, R., Ingersoll, A. J., Jordan, T. B., et al. (2026) · Cancer Research

Protein Degradation and InhibitorsAdvanced Breast Cancer Therapies

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