Schatz, Jonathan H.

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

Wolfe, A. L., Singh, K., Zhong, Y., Drewe, P., Rajasekhar, V. K., Sanghvi, V. R., Mavrakis, K. J., Jiang, M., Roderick, J. E., Van der Meulen, J., et al. (2014) · Nature

RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry

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Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

Schatz, J. H., Oricchio, E., Wolfe, A. L., Jiang, M., Linkov, I., Maragulia, J., Shi, W., Zhang, Z., Rajasekhar, V. K., Pagano, N. C., et al. (2011) · Journal of Experimental Medicine

PI3K/AKT/mTOR signaling in cancerLymphoma Diagnosis and Treatment

Cited by 119

Whole-genome sequencing reveals complex genomic features underlying anti-CD19 CAR T-cell treatment failures in lymphoma

Jain, M. D., Ziccheddu, B., Coughlin, C. A., Faramand, R., Griswold, A. J., Reid, K. M., Menges, M., Zhang, Y., Cen, L., Wang, X., et al. (2022) · Blood

CAR-T cell therapy researchLymphoma Diagnosis and Treatment

Cited by 91

NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy

Sanghvi, V. R., Mohan, P., Singh, K., Cao, L., Berishaj, M., Wolfe, A. L., Schatz, J. H., Lailler, N., de Stanchina, E., Viale, A., et al. (2021) · Cancers

Genomics, phytochemicals, and oxidative stressPI3K/AKT/mTOR signaling in cancer

Cited by 27

Oncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer Cells

Amin, A. D., Rajan, S. S., Groysman, M. J., Pongtornpipat, P., & schatz, J. H. (2015) · Biomarkers in Cancer

Lung Cancer Treatments and MutationsMelanoma and MAPK Pathways

Cited by 25