Srinivasan, Rahul

New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo

Srinivasan, R., Lu, T.-Y., Chai, H., Xu, J., Huang, B. S., Golshani, P., Coppola, G., & Khakh, B. S. (2016) · Neuron

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 443

Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning

Srinivasan, R., Pantoja, R., Moss, F. J., Mackey, E. D. W., Son, C. D., Miwa, J., & Lester, H. A. (2011) · Journal of General Physiology

Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation

Cited by 169

Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery

Lester, H. A., Xiao, C., Srinivasan, R., Son, C. D., Miwa, J., Pantoja, R., Banghart, M. R., Dougherty, D. A., Goate, A. M., & Wang, J. C. (2009) · The AAPS Journal

Nicotinic Acetylcholine Receptors StudyReceptor Mechanisms and Signaling

Cited by 163

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors

Henderson, B. J., Srinivasan, R., Nichols, W. A., Dilworth, C. N., Gutierrez, D. F., Mackey, E. D. W., McKinney, S., Drenan, R. M., Richards, C. I., & Lester, H. A. (2014) · Journal of General Physiology

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 78

Adeno-Associated Virus Expression of α-Synuclein as a Tool to Model Parkinson’s Disease: Current Understanding and Knowledge Gaps

Huntington, T. E., & Srinivasan, R. (2021) · Aging and disease

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 34

Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties

Huntington, T. E., & Srinivasan, R. (2021) · Cell Calcium

Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research

Cited by 31

Aging reduces calreticulin expression and alters spontaneous calcium signals in astrocytic endfeet of the mouse dorsolateral striatum

Zarate, S. M., Huntington, T. E., Bagher, P., & Srinivasan, R. (2023) · npj Aging

Barrier Structure and Function StudiesIon Channels and Receptors

Cited by 19

Systemically circulating 17β-estradiol enhances the neuroprotective effect of the smoking cessation drug cytisine in female parkinsonian mice

Zarate, S. M., Garcia, R. C., Pandey, G., & Srinivasan, R. (2025) · npj Parkinson's Disease

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 10

Heterogeneous brain region-specific responses to astrocytic mitochondrial DNA damage in mice

Ayala, D. A., Matarazzo, A., Seaberg, B. L., Patel, M., Tijerina, E., Matthews, C., Bizi, G., Brown, A., Ta, A., Rimer, M., et al. (2024) · Scientific Reports

Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research

Cited by 7

Mitochondrial DNA Damage in Substantia Nigra Pars Compacta Astrocytes Exacerbates Dopaminergic Neuron Loss in a 6-Hydroxydopamine Mouse Model of Parkinsonism

Ayala, D. A., Hall, G. M., Das, D., Tijerina, E., Villagran, L. L., Khan, Z., Paliwal, D., Anand, A., Rimer, M., & Srinivasan, R. (2026) · Cellular and Molecular Neurobiology

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 1