Abagyan, Ruben

METLIN—a metabolite mass spectral database

Smith, C. A., Maille, G. O., Want, E. J., Qin, C., Trauger, S. A., Brandon, T. R., Custodio, D. E., Abagyan, R., & Siuzdak, G. (2005) · Therapeutic Drug Monitoring

Metabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications

Cited by 2,226

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

Bowers, E. M., Yan, G., Mukherjee, C., Orry, A., Wang, L., Holbert, M. A., Crump, N. T., Hazzalin, C. A., Liszczak, G., Yuan, H., et al. (2010) · Chemistry & Biology

Histone Deacetylase Inhibitors ResearchComputational Drug Discovery Methods

Cited by 666

Flexible ligand docking to multiple receptor conformations: a practical alternative

Totrov, M., & Abagyan, R. (2008) · Current Opinion in Structural Biology

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 497

Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast

Isakoff, S. J., Cardozo, T., Andreev, J., Li, Z., Ferguson, K. M., Abagyan, R., Lemmon, M. A., Aronheim, A., & Skolnik, E. Y. (1998) · The EMBO Journal

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 324

Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

Bisson, W. H., Koch, D. C., O’Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., & Kolluri, S. K. (2009) · Journal of Medicinal Chemistry

Computational Drug Discovery MethodsToxic Organic Pollutants Impact

Cited by 149

Systematic exploitation of multiple receptor conformations for virtual ligand screening.

Bottegoni, G., Rocchia, W., Rueda, M., Abagyan, R., & Cavalli, A. (2011) · PLoS ONE

Computational Drug Discovery MethodsReceptor Mechanisms and Signaling

Cited by 96

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

Chan, J. D., Cupit, P. M., Gunaratne, G. S., McCorvy, J. D., Yang, Y., Stoltz, K., Webb, T. R., Dosa, P. I., Roth, B. L., Abagyan, R., et al. (2017) · Nature Communications

Parasites and Host InteractionsReceptor Mechanisms and Signaling

Cited by 69

Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins

DeForest, N., Kavitha, B., Hu, S., Isaac, R., Krohn, L., Wang, M., Du, X., De Arruda Saldanha, C., Gylys, J., Merli, E., et al. (2023) · Cell Genomics

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 21