Büning, Hildegard

Capsid modifications for targeting and improving the efficacy of AAV vectors

Büning, H., & Srivastava, A. (2019) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 260

Toll–Like Receptor 2–Mediated Innate Immune Response in Human Nonparenchymal Liver Cells Toward Adeno–Associated Viral Vectors

Hösel, M., Broxtermann, M., Janicki, H., Esser, K., Arzberger, S., Hartmann, P., Gillen, S., Kleeff, J., Stabenow, D., Odenthal, M., et al. (2012) · Hepatology

Virus-based gene therapy researchImmune Response and Inflammation

Cited by 219

Combinatorial engineering of a gene therapy vector: directed evolution of adeno‐associated virus

Perabo, L., Endell, J., King, S., Lux, K., Goldnau, D., Hallek, M., & Büning, H. (2006) · The Journal of Gene Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 136

Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders

Pavlou, M., Schön, C., Occelli, L. M., Rossi, A., Meumann, N., Boyd, R. F., Bartoe, J. T., Siedlecki, J., Gerhardt, M. J., Babutzka, S., et al. (2021) · EMBO Molecular Medicine

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 135

Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies

Huttner, N. A., Girod, A., Perabo, L., Edbauer, D., Kleinschmidt, J. A., Büning, H., & Hallek, M. (2003) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 124

Vector Uncoating Limits Adeno-Associated Viral Vector-Mediated Transduction of Human Dendritic Cells and Vector Immunogenicity

Rossi, A., Dupaty, L., Aillot, L., Zhang, L., Gallien, C., Hallek, M., Odenthal, M., Adriouch, S., Salvetti, A., & Büning, H. (2019) · Scientific Reports

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 85

Characterization of AAV vector particle stability at the single-capsid level

Bernaud, J., Rossi, A., Fis, A., Gardette, L., Aillot, L., Büning, H., Castelnovo, M., Salvetti, A., & Faivre-Moskalenko, C. (2018) · Journal of Biological Physics

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 83

Improving the Quality of Adeno-Associated Viral Vector Preparations: The Challenge of Product-Related Impurities

Schnödt, M., & Büning, H. (2017) · Human Gene Therapy Methods

Virus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects

Cited by 77

Optimization of stealth adeno-associated virus vectors by randomization of immunogenic epitopes

Maersch, S., Huber, A., Büning, H., Hallek, M., & Perabo, L. (2010) · Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 50

AAV capsid engineering identified two novel variants with improved in vivo tropism for cardiomyocytes

Rode, L., Bär, C., Groß, S., Rossi, A., Meumann, N., Viereck, J., Abbas, N., Xiao, K., Riedel, I., Gietz, A., et al. (2022) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 48

DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

Schnödt, M., Schmeer, M., Kracher, B., Krüsemann, C., Espinosa, L. E., Grünert, A., Fuchsluger, T., Rischmüller, A., Schleef, M., & Büning, H. (2016) · Molecular Therapy - Nucleic Acids

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 39

Modifying immune responses to adeno-associated virus vectors by capsid engineering

Bentler, M., Hardet, R., Ertelt, M., Rudolf, D., Kaniowska, D., Schneider, A., Vondran, F. W. R., Schoeder, C. T., Delphin, M., Lucifora, J., et al. (2023) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 34