Lu, Yuancheng Ryan

Reprogramming to recover youthful epigenetic information and restore vision

Lu, Y., Brommer, B., Tian, X., Krishnan, A., Meer, M., Wang, C., Vera, D. L., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2020) · Nature

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 820

Loss of epigenetic information as a cause of mammalian aging

Yang, J.-H., Hayano, M., Griffin, P. T., Amorim, J. A., Bonkowski, M. S., Apostolides, J. K., Salfati, E. L., Blanchette, M., Munding, E. M., Bhakta, M., et al. (2023) · Cell

Genetics, Aging, and Longevity in Model OrganismsEpigenetics and DNA Methylation

Cited by 643

Impairment of an endothelial NAD(+)-H2S signaling network is a reversible cause of vascular aging

Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., Kim, L.-J., Osborne, B., Joshi, S., Lu, Y., et al. (2018) · Cell

Nitric Oxide and Endothelin EffectsSirtuins and Resveratrol in Medicine

Cited by 496

The Information Theory of Aging

Lu, Y. R., Tian, X., & Sinclair, D. A. (2023) · Nature Aging

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 141

Gene Therapy-Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice

Macip, C. C., Hasan, R., Hoznek, V., Kim, J., Lu, Y. R., Metzger, L. E., Sethna, S., & Davidsohn, N. (2024) · Cellular Reprogramming

Genetics, Aging, and Longevity in Model OrganismsPluripotent Stem Cells Research

Cited by 95

Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma

Karg, M. M., Lu, Y. R., Refaian, N., Cameron, J., Hoffmann, E., Hoppe, C., Shirahama, S., Shah, M., Krasniqi, D., Krishnan, A., et al. (2023) · Cellular Reprogramming

Retinal Development and DisordersGlaucoma and retinal disorders

Cited by 34

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

Lu, Y., Krishnan, A., Brommer, B., Tian, X., Meer, M., Vera, D. L., Wang, C., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Epigenetics and DNA MethylationRetinal Development and Disorders

Cited by 20