Caulfield, Thomas R.

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Yamazaki, Y., Zhao, N., Caulfield, T. R., Liu, C.-C., & Bu, G. (2019) · Nature Reviews Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,425

PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson’s Disease Pathobiology?

Truban, D., Hou, X., Caulfield, T. R., Fiesel, F. C., & Springer, W. (2016) · Journal of Parkinson’s Disease

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 237

(Patho‐)physiological relevance of PINK1‐dependent ubiquitin phosphorylation

Fiesel, F. C., Ando, M., Hudec, R., Hill, A. R., Castanedes‐Casey, M., Caulfield, T. R., Moussaud‐Lamodière, E. L., Stankowski, J. N., Bauer, P. O., Lorenzo‐Betancor, O., et al. (2015) · The EMBO Reports

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 185

APOE3 -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia

Liu, C.-C., Murray, M. E., Li, X., Zhao, N., Wang, N., Heckman, M. G., Shue, F., Martens, Y., Li, Y., Raulin, A.-C., et al. (2021) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin: HUMAN MUTATION

Fiesel, F. C., Caulfield, T. R., Moussaud-Lamodière, E. L., Ogaki, K., Dourado, D. F. A. R., Flores, S. C., Ross, O. A., & Springer, W. (2015) · Human Mutation

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 89

Substitution of PINK1 Gly411 modulates substrate receptivity and turnover

Fiesel, F. C., Fričová, D., Hayes, C. S., Coban, M. A., Hudec, R., Bredenberg, J. M., Broadway, B. J., Markham, B. N., Yan, T., Boneski, P. K., et al. (2023) · Autophagy

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 29