Craigie, Robert

Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases

Dyda, F., Hickman, A. B., Jenkins, T. M., Engelman, A., Craigie, R., & Davies, D. R. (1994) · Science

HIV/AIDS drug development and treatmentEnzyme Structure and Function

Cited by 810

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

Engelman, A., Mizuuchi, K., & Craigie, R. (1991) · Cell

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 655

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

Engelman, A., & Craigie, R. (1992) · Journal of Virology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 519

Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication

Engelman, A., Englund, G., Orenstein, J. M., Martin, M. A., & Craigie, R. (1995) · Journal of Virology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 445

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

Bushman, F. D., & Craigie, R. (1991) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 410

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

Craigie, R., Fujiwara, T., & Bushman, F. (1990) · Cell

T-cell and Retrovirus StudiesHIV Research and Treatment

Cited by 409

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

Cai, M., Zheng, R., Caffrey, M., Craigie, R., Clore, G. M., & Gronenborn, A. M. (1997) · Nature Structural Biology

Protein Structure and DynamicsHIV/AIDS drug development and treatment

Cited by 342

Retroviral DNA integration directed by HIV integration protein in vitro

Bushman, F. D., Fujiwara, T., & Craigie, R. (1990) · Science

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 338

HIV DNA Integration

Craigie, R., & Bushman, F. D. (2012) · Cold Spring Harbor Perspectives in Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 327

Solution Structure of the DNA Binding Domain of HIV-1 Integrase

Lodi, P. J., Ernst, J. A., Kuszewski, J., Hickman, A. B., Engelman, A., Craigie, R., Clore, G. M., & Gronenborn, A. M. (1995) · Biochemistry

Protein Structure and DynamicsHIV/AIDS drug development and treatment

Cited by 300

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome

Passos, D. O., Li, M., Yang, R., Rebensburg, S. V., Ghirlando, R., Jeon, Y., Shkriabai, N., Kvaratskhelia, M., Craigie, R., & Lyumkis, D. (2017) · Science

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 202

Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration

Fujiwara, T., & Craigie, R. (1989) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchT-cell and Retrovirus Studies

Cited by 109

Structural basis for strand-transfer inhibitor binding to HIV intasomes

Passos, D. O., Li, M., Jóźwik, I. K., Zhao, X. Z., Santos-Martins, D., Yang, R., Smith, S. J., Jeon, Y., Forli, S., Hughes, S. H., et al. (2020) · Science

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 106

HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro

Li, M., Yang, R., Chen, X., Wang, H., Ghirlando, R., Dimitriadis, E. K., & Craigie, R. (2024) · Journal of Molecular Biology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 18

A Peptide Derived from Lens Epithelium–Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies

Li, M., Chen, X., Wang, H., Jurado, K. A., Engelman, A. N., & Craigie, R. (2020) · Journal of Molecular Biology

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 18

HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration

Li, M., Li, Z., Chen, X., Cui, Y., Engelman, A. N., & Craigie, R. (2024) · Viruses

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 12