DeFranco, Donald B.

Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures

Stanciu, M., Wang, Y., Kentor, R., Burke, N., Watkins, S., Kress, G., Reynolds, I., Klann, E., Angiolieri, M. R., Johnson, J. W., et al. (2000) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingRedox biology and oxidative stress

Cited by 539

Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement

Pratt, W. B., Galigniana, M. D., Harrell, J. M., & DeFranco, D. B. (2004) · Cellular Signalling

Heat shock proteins researchNuclear Structure and Function

Cited by 285

Proteasomal inhibition enhances glucocorticoid receptor transactivation and alters its subnuclear trafficking

Deroo, B. J., Rentsch, C., Sampath, S., Young, J., DeFranco, D. B., & Archer, T. K. (2002) · Molecular and Cellular Biology

Estrogen and related hormone effectsUbiquitin and proteasome pathways

Cited by 164

Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons

Levinthal, D. J., & DeFranco, D. B. (2005) · Journal of Biological Chemistry

Protein Tyrosine PhosphatasesRedox biology and oxidative stress

Cited by 126

Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation

Samarasinghe, R. A., Di Maio, R., Volonte, D., Galbiati, F., Lewis, M., Romero, G., & DeFranco, D. B. (2011) · Proceedings of the National Academy of Sciences

Connexins and lens biologyCaveolin-1 and cellular processes

Cited by 120

Glucocorticoid repression of the reproductive axis: Effects on GnRH and gonadotropin subunit mRNA levels

Gore, A. C., Attardi, B., & DeFranco, D. B. (2006) · Molecular and Cellular Endocrinology

Hypothalamic control of reproductive hormonesStress Responses and Cortisol

Cited by 104

Alternative Effects of the Ubiquitin-Proteasome Pathway on Glucocorticoid Receptor Down-Regulation and Transactivation Are Mediated by CHIP, an E3 Ligase

Wang, X., & DeFranco, D. B. (2005) · Molecular Endocrinology

Ubiquitin and proteasome pathwaysEstrogen and related hormone effects

Cited by 77

Mechanisms of disease: regulation of glucocorticoid and receptor levels – impact on the metabolic syndrome

Witchel, S. F., & DeFranco, D. B. (2006) · Nature Clinical Practice Endocrinology & Metabolism

Estrogen and related hormone effectsAdrenal Hormones and Disorders

Cited by 58

Cooperativity and complementarity: Synergies in non-classical and classical glucocorticoid signaling

Samarasinghe, R. A., Witchell, S. F., & DeFranco, D. B. (2012) · Cell Cycle

Estrogen and related hormone effectsReceptor Mechanisms and Signaling

Cited by 54

Minireview: the impact of antenatal therapeutic synthetic glucocorticoids on the developing fetal brain

Peffer, M. E., Zhang, J. Y., Umfrey, L., Rudine, A. C., Monaghan, A. P., & DeFranco, D. B. (2015) · Molecular Endocrinology

Birth, Development, and HealthNeonatal and fetal brain pathology

Cited by 30

A novel in situ assay for the identification and characterization of soluble nuclear mobility factors

Elbi, C., Walker, D. A., Lewis, M., Romero, G., Sullivan, W. P., Toft, D. O., Hager, G. L., & DeFranco, D. B. (2004) · Science s STKE

Nuclear Structure and FunctionAdvanced Fluorescence Microscopy Techniques

Cited by 17