Laitinen, Tuomo

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

Pantsar, T., Rissanen, S., Dauch, D., Laitinen, T., Vattulainen, I., & Poso, A. (2018) · PLOS Computational Biology

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 85

Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells

Deen, A. J., Adinolfi, S., Härkönen, J., Patinen, T., Liu, X., Laitinen, T., Takabe, P., Kainulainen, K., Pasonen-Seppänen, S., Gawriyski, L. M., et al. (2024) · Redox Biology

Genomics, phytochemicals, and oxidative stressNF-κB Signaling Pathways

Cited by 27

Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells

Deen, A. J., Adinolfi, S., Härkönen, J., Patinen, T., Liu, X., Laitinen, T., Takabe, P., Kainulainen, K., Pasonen-Seppänen, S., Gawriyski, L. M., et al. (2023) · Redox Biology

Genomics, phytochemicals, and oxidative stressNF-κB Signaling Pathways

Cited by 27

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Karim, M., Mishra, M., Lo, C.-W., Saul, S., Cagirici, H. B., Gourdelier, M., Ghita, L., Ojha, A., Tran, D. H. N., Agrawal, A., et al. (2025) · Nature Communications

SARS-CoV-2 and COVID-19 ResearchAutophagy in Disease and Therapy

Cited by 16