Roodman, G. David

Pathogenesis of myeloma bone disease

Roodman, G. D. (2009) · Leukemia

Multiple Myeloma Research and TreatmentsBone Metabolism and Diseases

Cited by 398

Paget disease of bone.

Roodman, G. D., & Windle, J. J. (2005) · Journal of Clinical Investigation

Bone Metabolism and DiseasesAlkaline Phosphatase Research Studies

Cited by 340

Multiple myeloma bone disease: pathophysiology of osteoblast inhibition

Giuliani, N., Rizzoli, V., & Roodman, G. D. (2006) · Blood

Multiple Myeloma Research and TreatmentsBone Metabolism and Diseases

Cited by 302

Osteoclasts are important for bone angiogenesis

Cackowski, F. C., Anderson, J. L., Patrene, K. D., Choksi, R. J., Shapiro, S. D., Windle, J. J., Blair, H. C., & Roodman, G. D. (2010) · Blood

Bone Metabolism and DiseasesAngiogenesis and VEGF in Cancer

Cited by 188

Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget’s disease of bone.

Menaa, C., Reddy, S. V., Kurihara, N., Maeda, H., Anderson, D., Cundy, T., Cornish, J., Singer, F. R., Bruder, J. M., & Roodman, G. D. (2000) · Journal of Clinical Investigation

Bone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research

Cited by 154

In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2

Maes, K., Nemeth, E., Roodman, G. D., Huston, A., Esteve, F., Freytes, C., Callander, N., Katodritou, E., Tussing-Humphreys, L., Rivera, S., et al. (2010) · Blood

Iron Metabolism and DisordersCytokine Signaling Pathways and Interactions

Cited by 132

Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease

Kurihara, N., Hiruma, Y., Zhou, H., Subler, M. A., Dempster, D. W., Singer, F. R., Reddy, S. V., Gruber, H. E., Windle, J. J., & Roodman, G. D. (2007) · Journal of Clinical Investigation

Bone Metabolism and DiseasesBone health and treatments

Cited by 127

Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiation.

Takahashi, S., Goldring, S., Katz, M., Hilsenbeck, S., Williams, R., & Roodman, G. D. (1995) · Journal of Clinical Investigation

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 125

Human bone marrow myeloma cells express RANKL.

Sezer, O., Heider, U., Jakob, C., Eucker, J., Possinger, K., & Roodman, G. D. (2002) · Journal of Clinical Oncology

Multiple Myeloma Research and TreatmentsBone Metabolism and Diseases

Cited by 104

A SQSTM1/p62 mutation linked to Paget’s disease increases the osteoclastogenic potential of the bone microenvironment

Hiruma, Y., Kurihara, N., Subler, M. A., Zhou, H., Boykin, C. S., Zhang, H., Ishizuka, S., Dempster, D. W., Roodman, G. D., & Windle, J. J. (2008) · Human Molecular Genetics

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 90

EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma–Induced Epigenetic Suppression of Osteoblast Differentiation

Adamik, J., Jin, S., Sun, Q., Zhang, P., Weiss, K. R., Anderson, J. L., Silbermann, R., Roodman, G. D., & Galson, D. L. (2017) · Molecular Cancer Research

Multiple Myeloma Research and TreatmentsBone Metabolism and Diseases

Cited by 73

A cost-effectiveness analysis of denosumab for the prevention of skeletal-related events in patients with multiple myeloma in the United States of America

Raje, N., Roodman, G. D., Willenbacher, W., Shimizu, K., García-Sanz, R., Terpos, E., Kennedy, L., Sabatelli, L., Intorcia, M., & Hechmati, G. (2018) · Journal of Medical Economics

Bone health and treatmentsHealth Systems, Economic Evaluations, Quality of Life

Cited by 25

An International, Randomized, Double Blind Trial Comparing Denosumab With Zoledronic Acid (ZA) for the Treatment of Bone Disease in Patients (Pts) With Newly Diagnosed Multiple Myeloma

Raje, N., Terpos, E., Willenbacher, W., Shimizu, K., Garcia-Sanz, R., Durie, B., Legiec, W., Krejci, M., Laribi, K., Zhu, L., et al. (2017) · Clinical Lymphoma Myeloma and Leukemia

Bone health and treatmentsMultiple Myeloma Research and Treatments

Cited by 14