Kono, Hajime

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., et al. (2010) · Nature

Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases

Cited by 4,026

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A., & Latz, E. (2008) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,065

How dying cells alert the immune system to danger

Kono, H., & Rock, K. L. (2008) · Nature Reviews Immunology

Immune Response and InflammationCell death mechanisms and regulation

Cited by 1,737

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

Chen, C.-J., Kono, H., Golenbock, D., Reed, G., Akira, S., & Rock, K. L. (2007) · Nature Medicine

Immune Response and InflammationInflammasome and immune disorders

Cited by 876

The Sterile Inflammatory Response

Rock, K. L., Latz, E., Ontiveros, F., & Kono, H. (2010) · Annual Review of Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 865

Uric acid promotes an acute inflammatory response to sterile cell death in mice

Kono, H., Chen, C.-J., Ontiveros, F., & Rock, K. L. (2010) · Journal of Clinical Investigation

Gout, Hyperuricemia, Uric AcidImmune Response and Inflammation

Cited by 337

Identification of the Cellular Sensor That Stimulates the Inflammatory Response to Sterile Cell Death

Kono, H., Karmarkar, D., Iwakura, Y., & Rock, K. L. (2010) · The Journal of Immunology

Immune Response and InflammationInflammasome and immune disorders

Cited by 101