Ruan, Jianbin

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Liu, X., Zhang, Z., Ruan, J., Pan, Y., Magupalli, V. G., Wu, H., & Lieberman, J. (2016) · Nature

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 3,202

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

Lu, A., Magupalli, V. G., Ruan, J., Yin, Q., Atianand, M. K., Vos, M. R., Schröder, G. F., Fitzgerald, K. A., Wu, H., & Egelman, E. H. (2014) · Cell

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,353

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

Hu, J. J., Liu, X., Xia, S., Zhang, Z., Zhang, Y., Zhao, J., Ruan, J., Luo, X., Lou, X., Bai, Y., et al. (2020) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,145

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

Evavold, C. L., Ruan, J., Tan, Y., Xia, S., Wu, H., & Kagan, J. C. (2018) · Immunity

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,115

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

Zanoni, I., Tan, Y., Di Gioia, M., Broggi, A., Ruan, J., Shi, J., Donado, C. A., Shao, F., Wu, H., Springstead, J. R., et al. (2016) · Science

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 583

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

Bian, C., Xu, C., Ruan, J., Lee, K. K., Burke, T. L., Tempel, W., Barsyte, D., Li, J., Wu, M., Zhou, B. O., et al. (2011) · The EMBO Journal

Genomics and Chromatin DynamicsCancer-related gene regulation

Cited by 281