Lindström, Mikael S.

Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation

Itahana, K., Mao, H., Jin, A., Itahana, Y., Clegg, H. V., Lindström, M. S., Bhat, K. P., Godfrey, V. L., Evan, G. I., & Zhang, Y. (2007) · Cancer Cell

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

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MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation

Jackson, M. W., Lindström, M. S., & Berberich, S. J. (2001) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysHeat shock proteins research

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Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET

Kanellis, D. C., Zisi, A., Skrott, Z., Lemmens, B., Espinoza, J. A., Kosar, M., Björkman, A., Li, X., Arampatzis, S., Bartkova, J., et al. (2023) · Cell Death & Differentiation

Cancer-related Molecular PathwaysCell death mechanisms and regulation

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Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling

Wenson, L., Heldin, J., Martin, M., Erbilgin, Y., Salman, B., Sundqvist, A., Schaal, W., Sandbaumhüter, F. A., Jansson, E. T., Chen, X., et al. (2025) · Nature Communications

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

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