Choi, Kang-Yell

Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway

Jeong, W.-J., Ro, E. J., & Choi, K.-Y. (2018) · npj Precision Oncology

Wnt/β-catenin signaling in development and cancerColorectal Cancer Treatments and Studies

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MEK1/2 Inhibitors AS703026 and AZD6244 May Be Potential Therapies for KRAS Mutated Colorectal Cancer That Is Resistant to EGFR Monoclonal Antibody Therapy

Yoon, J., Koo, K.-H., & Choi, K.-Y. (2011) · Cancer Research

Colorectal Cancer Treatments and StudiesMelanoma and MAPK Pathways

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Interaction of the Wnt/β-catenin and RAS-ERK pathways involving co-stabilization of both β-catenin and RAS plays important roles in the colorectal tumorigenesis

Lee, S.-K., Hwang, J.-H., & Choi, K.-Y. (2018) · Advances in Biological Regulation

Wnt/β-catenin signaling in development and cancerColorectal Cancer Treatments and Studies

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Screening-based approaches to identify small molecules that inhibit protein–protein interactions

Choi, S., & Choi, K.-Y. (2017) · Expert Opinion on Drug Discovery

Computational Drug Discovery MethodsChemical Synthesis and Analysis

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Identification of Ras-degrading small molecules that inhibit the transformation of colorectal cancer cells independent of β-catenin signaling

Shin, W., Lee, S.-K., Hwang, J.-H., Park, J.-C., Cho, Y.-H., Ro, E. J., Song, Y., Seo, H. R., & Choi, K.-Y. (2018) · Experimental & Molecular Medicine

Protein Kinase Regulation and GTPase SignalingWnt/β-catenin signaling in development and cancer

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