Ponsioen, Bas

Sequential cancer mutations in cultured human intestinal stem cells

Drost, J., van Jaarsveld, R. H., Ponsioen, B., Zimberlin, C., van Boxtel, R., Buijs, A., Sachs, N., Overmeer, R. M., Offerhaus, G. J., Begthel, H., et al. (2015) · Nature

Cancer Cells and MetastasisGenetic factors in colorectal cancer

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An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper, O., de Witte, C. J., Lõhmussaar, K., Valle-Inclan, J. E., Hami, N., Kester, L., Balgobind, A. V., Korving, J., Proost, N., Begthel, H., et al. (2019) · Nature Medicine

Ovarian cancer diagnosis and treatmentCancer Cells and Metastasis

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Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

Verissimo, C. S., Overmeer, R. M., Ponsioen, B., Drost, J., Mertens, S., Verlaan-Klink, I., Gerwen, B. V., van der Ven, M., Wetering, M. V. D., Egan, D. A., et al. (2016) · eLife

Colorectal Cancer Treatments and StudiesProtein Kinase Regulation and GTPase Signaling

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GSK-3 Is Activated by the Tyrosine Kinase Pyk2 during LPA1-mediated Neurite Retraction

Sayas, C. L., Ariaens, A., Ponsioen, B., & Moolenaar, W. H. (2006) · Molecular Biology of the Cell

Protein Kinase Regulation and GTPase SignalingSphingolipid Metabolism and Signaling

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Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

Vellinga, T. T., den Uil, S., Rinkes, I. H. B., Marvin, D., Ponsioen, B., Alvarez-Varela, A., Fatrai, S., Scheele, C., Zwijnenburg, D. A., Snippert, H., et al. (2016) · Oncogene

Cancer Cells and MetastasisTGF-β signaling in diseases

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