Boymans, Sander

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

Schwank, G., Koo, B.-K., Sasselli, V., Dekkers, J. F., Heo, I., Demircan, T., Sasaki, N., Boymans, S., Cuppen, E., van der Ent, C. K., et al. (2013) · Cell Stem Cell

CRISPR and Genetic EngineeringCystic Fibrosis Research Advances

Cited by 1,424

Tissue-specific mutation accumulation in human adult stem cells during life

Blokzijl, F., de Ligt, J., Jager, M., Sasselli, V., Roerink, S., Sasaki, N., Huch, M., Boymans, S., Kuijk, E., Prins, P., et al. (2016) · Nature

Cancer Genomics and DiagnosticsGenetic factors in colorectal cancer

Cited by 935

The mutational impact of culturing human pluripotent and adult stem cells

Kuijk, E., Jager, M., van der Roest, B., Locati, M. D., Van Hoeck, A., Korzelius, J., Janssen, R., Besselink, N., Boymans, S., van Boxtel, R., et al. (2020) · Nature Communications

Pluripotent Stem Cells ResearchCancer Genomics and Diagnostics

Cited by 124

Genomic landscape of rat strain and substrain variation

Hermsen, R., de Ligt, J., Spee, W., Blokzijl, F., Schäfer, S., Adami, E., Boymans, S., Flink, S., van Boxtel, R., van der Weide, R. H., et al. (2015) · BMC Genomics

Genomics and Phylogenetic StudiesGenetic Mapping and Diversity in Plants and Animals

Cited by 93

Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures

Jager, M., Blokzijl, F., Sasselli, V., Boymans, S., Janssen, R., Besselink, N., Clevers, H., van Boxtel, R., & Cuppen, E. (2018) · Nature Protocols

Cancer Genomics and DiagnosticsSingle-cell and spatial transcriptomics

Cited by 66