Mariani, Nicole

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Mancuso, R., Fryatt, G., Cleal, M., Obst, J., Pipi, E., Monzón-Sandoval, J., Ribe, E., Winchester, L., Webber, C., Nevado, A., et al. (2019) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial

Nettis, M. A., Lombardo, G., Hastings, C., Zajkowska, Z., Mariani, N., Nikkheslat, N., Worrell, C., Enache, D., McLaughlin, A., Kose, M., et al. (2021) · Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

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Childhood trauma, HPA axis activity and antidepressant response in patients with depression

Nikkheslat, N., McLaughlin, A. P., Hastings, C., Zajkowska, Z., Nettis, M. A., Mariani, N., Enache, D., Lombardo, G., Pointon, L., Cowen, P. J., et al. (2020) · Brain, Behavior, and Immunity

Stress Responses and CortisolChild Abuse and Trauma

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FoxO1, A2M, and TGF-Β1: Three Novel Genes Predicting Depression in Gene X Environment Interactions Are Identified Using Cross-Species and Cross-Tissues Transcriptomic and MiRNomic Analyses

Cattaneo, A., Cattane, N., Malpighi, C., Czamara, D., Suarez, A., Mariani, N., Kajantie, E., Luoni, A., Eriksson, J. G., Lahti, J., et al. (2018) · Molecular Psychiatry

Genetic Associations and EpidemiologyStress Responses and Cortisol

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Vicente-Rodríguez, M., Mancuso, R., Peris-Yague, A., Simmons, C., NIMA Consortium, Wlazly, D., Dickinson, A., Foster, A., Knight, C., Leckey, C., et al. (2023) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsPrion Diseases and Protein Misfolding

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Ketamine Prevents Inflammation-Induced Reduction of Human Hippocampal Neurogenesis via Inhibiting the Production of Neurotoxic Metabolites of the Kynurenine Pathway

Mandal, G., Kirkpatrick, M., Alboni, S., Mariani, N., Pariante, C. M., & Borsini, A. (2024) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

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