Joshi, Amit U.

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

Joshi, A. U., Minhas, P. S., Liddelow, S. A., Haileselassie, B., Andreasson, K. I., Dorn, G. W., & Mochly-Rosen, D. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMitochondrial Function and Pathology

Cited by 571

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

Minhas, P. S., Latif-Hernandez, A., McReynolds, M. R., Durairaj, A. S., Wang, Q., Rubin, A., Joshi, A. U., He, J. Q., Gauba, E., Liu, L., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 526

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation

Minhas, P. S., Liu, L., Moon, P. K., Joshi, A. U., Dove, C., Mhatre, S., Contrepois, K., Wang, Q., Lee, B. A., Coronado, M., et al. (2019) · Nature Immunology

Sirtuins and Resveratrol in MedicineTryptophan and brain disorders

Cited by 501

VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease

Guo, X., Sun, X., Hu, D., Wang, Y.-J., Fujioka, H., Vyas, R., Chakrapani, S., Joshi, A. U., Luo, Y., Mochly-Rosen, D., et al. (2016) · Nature Communications

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 200

Potential biomarkers to follow the progression and treatment response of Huntington’s disease

Disatnik, M.-H., Joshi, A. U., Saw, N. L., Shamloo, M., Leavitt, B. R., Qi, X., & Mochly-Rosen, D. (2016) · Journal of Experimental Medicine

Genetic Neurodegenerative DiseasesMitochondrial Function and Pathology

Cited by 58