Frew, Ian J.

HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice

Hoefflin, R., Harlander, S., Schäfer, S., Metzger, P., Kuo, F., Schönenberger, D., Adlesic, M., Peighambari, A., Seidel, P., Chen, C.-Y., et al. (2020) · Nature Communications

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A binding motif for Siah ubiquitin ligase

House, C. M., Frew, I. J., Huang, H.-L., Wiche, G., Traficante, N., Nice, E., Catimel, B., & Bowtell, D. D. L. (2003) · Proceedings of the National Academy of Sciences

Ubiquitin and proteasome pathwaysWnt/β-catenin signaling in development and cancer

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Combined mutation in Vhl, Trp53 and Rb1 causes clear cell renal cell carcinoma in mice

Harlander, S., Schönenberger, D., Toussaint, N. C., Prummer, M., Catalano, A., Brandt, L., Moch, H., Wild, P. J., & Frew, I. J. (2017) · Nature Medicine

Renal cell carcinoma treatmentCancer, Hypoxia, and Metabolism

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Hedgehog pathway inhibitors promote adaptive immune responses in basal cell carcinoma

Otsuka, A., Dreier, J., Cheng, P. F., Nägeli, M., Lehmann, H., Felderer, L., Frew, I. J., Matsushita, S., Levesque, M. P., & Dummer, R. (2015) · Clinical Cancer Research

Hedgehog Signaling Pathway StudiesNonmelanoma Skin Cancer Studies

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