Sirkis, Daniel W.

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

Vargas, M. R., Johnson, D. A., Sirkis, D. W., Messing, A., & Johnson, J. A. (2008) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchGenomics, phytochemicals, and oxidative stress

Cited by 479

Dissecting the clinical heterogeneity of early-onset Alzheimer’s disease

Sirkis, D. W., Bonham, L. W., Johnson, T. P., La Joie, R., & Yokoyama, J. S. (2022) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 151

The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease

Bonham, L. W., Sirkis, D. W., & Yokoyama, J. S. (2019) · Frontiers in Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 83

Rare TREM2 variants associated with Alzheimer’s disease display reduced cell surface expression

Sirkis, D. W., Bonham, L. W., Aparicio, R. E., Geier, E. G., Ramos, E. M., Wang, Q., Karydas, A., Miller, Z. A., Miller, B. L., Coppola, G., et al. (2016) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 61

Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers

Wu, S., Hernandez Villegas, N. C., Sirkis, D. W., Thomas-Wright, I., Wade-Martins, R., & Schekman, R. (2023) · eLife

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 52

Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia

Geier, E. G., Bourdenx, M., Storm, N. J., Cochran, J. N., Sirkis, D. W., Hwang, J.-H., Bonham, L. W., Ramos, E. M., Diaz, A., Van Berlo, V., et al. (2019) · Acta Neuropathologica

Alzheimer's disease research and treatmentsLysosomal Storage Disorders Research

Cited by 39

Immunological signatures in frontotemporal lobar degeneration

Sirkis, D. W., Bonham, L. W., Karch, C. M., & Yokoyama, J. S. (2019) · Current Opinion in Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 14

Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer’s disease

Bonham, L. W., Sirkis, D. W., Fan, J., Aparicio, R. E., Tse, M., Ramos, E. M., Wang, Q., Coppola, G., Rosen, H. J., Miller, B. L., et al. (2017) · Neurocase

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 10