Fowler, Benjamin J.

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Kaneko, H., Dridi, S., Tarallo, V., Gelfand, B. D., Fowler, B. J., Cho, W. G., Kleinman, M. E., Ponicsan, S. L., Hauswirth, W. W., Chiodo, V. A., et al. (2011) · Nature

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 601

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88

Tarallo, V., Hirano, Y., Gelfand, B. D., Dridi, S., Kerur, N., Kim, Y., Cho, W. G., Kaneko, H., Fowler, B. J., Bogdanovich, S., et al. (2012) · Cell

Inflammasome and immune disordersRetinal Diseases and Treatments

Cited by 592

Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity

Fowler, B. J., Gelfand, B. D., Kim, Y., Kerur, N., Tarallo, V., Hirano, Y., Amarnath, S., Fowler, D. H., Radwan, M., Young, M. T., et al. (2014) · Science

Inflammasome and immune disordersAdenosine and Purinergic Signaling

Cited by 225

ERK1/2 activation is a therapeutic target in age-related macular degeneration

Dridi, S., Hirano, Y., Tarallo, V., Kim, Y., Fowler, B. J., Ambati, B. K., Bogdanovich, S., Chiodo, V. A., Hauswirth, W. W., Kugel, J. F., et al. (2012) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 105

Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development

Ambati, J., Magagnoli, J., Leung, H., Wang, S.-B., Andrews, C. A., Fu, D., Pandey, A., Sahu, S., Narendran, S., Hirahara, S., et al. (2020) · Nature Communications

Inflammasome and immune disordersAdipokines, Inflammation, and Metabolic Diseases

Cited by 66

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration

Fukuda, S., Varshney, A., Fowler, B. J., Wang, S.-B., Narendran, S., Ambati, K., Yasuma, T., Magagnoli, J., Leung, H., Hirahara, S., et al. (2021) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsRetinal Diseases and Treatments

Cited by 65