Petretto, Enrico

A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation

Grubman, A., Chew, G., Ouyang, J. F., Sun, G., Choo, X. Y., McLean, C., Simmons, R. K., Buckberry, S., Vargas-Landin, D. B., Poppe, D., et al. (2019) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 956

IL-11 is a crucial determinant of cardiovascular fibrosis

Schafer, S., Viswanathan, S., Widjaja, A. A., Lim, W.-W., Moreno-Moral, A., DeLaughter, D. M., Ng, B., Patone, G., Chow, K., Khin, E., et al. (2017) · Nature

Cardiac Fibrosis and RemodelingTGF-β signaling in diseases

Cited by 639

Repeatability of published microarray gene expression analyses

Ioannidis, J. P. A., Allison, D. B., Ball, C. A., Coulibaly, I., Cui, X., Culhane, A. C., Falchi, M., Furlanello, C., Game, L., Jurman, G., et al. (2009) · Nature Genetics

Gene expression and cancer classificationScientific Computing and Data Management

Cited by 551

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

Grubman, A., Choo, X. Y., Chew, G., Ouyang, J. F., Sun, G., Croft, N. P., Rossello, F. J., Simmons, R., Buckberry, S., Landin, D. V., et al. (2021) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 357

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

Cardiogenics Consortium, Heinig, M., Petretto, E., Wallace, C., Bottolo, L., Rotival, M., Lu, H., Li, Y., Sarwar, R., Langley, S. R., et al. (2010) · Nature

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 283

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

Widjaja, A. A., Lim, W.-W., Viswanathan, S., Chothani, S., Corden, B., Dasan, C. M., Goh, J. W. T., Lim, R., Singh, B. K., Tan, J., et al. (2024) · Nature

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 238

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

Cuartero, S., Weiss, F. D., Dharmalingam, G., Guo, Y., Ing-Simmons, E., Masella, S., Robles-Rebollo, I., Xiao, X., Wang, Y.-F., Barozzi, I., et al. (2018) · Nature Immunology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 210

Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

Krishnan, M. L., Van Steenwinckel, J., Schang, A.-L., Yan, J., Arnadottir, J., Le Charpentier, T., Csaba, Z., Dournaud, P., Cipriani, S., Auvynet, C., et al. (2017) · Nature Communications

Neonatal and fetal brain pathologyNeuroinflammation and Neurodegeneration Mechanisms

Cited by 105

Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk

Moreno-Moral, A., Bagnati, M., Koturan, S., Ko, J.-H., Fonseca, C., Harmston, N., Game, L., Martin, J., Ong, V., Abraham, D. J., et al. (2018) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 78

Genetic influences on brain gene expression in rats selected for tameness and aggression

Heyne, H. O., Lautenschläger, S., Nelson, R., Besnier, F., Rotival, M., Cagan, A., Kozhemyakina, R., Plyusnina, I. Z., Trut, L., Carlborg, Ö., et al. (2014) · Genetics

Human-Animal Interaction StudiesAnimal Behavior and Reproduction

Cited by 72

Multi-tissue Analysis of Co-expression Networks by Higher-Order Generalized Singular Value Decomposition Identifies Functionally Coherent Transcriptional Modules

Xiao, X., Moreno-Moral, A., Rotival, M., Bottolo, L., & Petretto, E. (2014) · PLoS Genetics

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 63

Mouse and human microglial phenotypes in Alzheimer’s disease are controlled by amyloid plaque phagocytosis through Hif1α

Grubman, A., Choo, X. Y., Chew, G., Ouyang, J. F., Sun, G., Croft, N. P., Rossello, F. J., Simmons, R., Buckberry, S., Landin, D. V., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 7