Horst, David

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

Meinhardt, J., Radke, J., Dittmayer, C., Franz, J., Thomas, C., Mothes, R., Laue, M., Schneider, J., Brünink, S., Greuel, S., et al. (2021) · Nature Neuroscience

Long-Term Effects of COVID-19Olfactory and Sensory Function Studies

Cited by 1,458

IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

Rokavec, M., Öner, M. G., Li, H., Jackstadt, R., Jiang, L., Lodygin, D., Kaller, M., Horst, D., Ziegler, P. K., Schwitalla, S., et al. (2014) · Journal of Clinical Investigation

MicroRNA in disease regulationCytokine Signaling Pathways and Interactions

Cited by 753

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Wendisch, D., Dietrich, O., Mari, T., von Stillfried, S., Ibarra, I. L., Mittermaier, M., Mache, C., Chua, R. L., Knoll, R., Timm, S., et al. (2021) · Cell

COVID-19 Clinical Research StudiesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 528

Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors

Schwitalla, S., Ziegler, P. K., Horst, D., Becker, V., Kerle, I., Begus-Nahrmann, Y., Lechel, A., Rudolph, K. L., Langer, R., Slotta-Huspenina, J., et al. (2013) · Cancer Cell

Cancer-related Molecular PathwaysGenetic factors in colorectal cancer

Cited by 296

Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix

Jiang, H., Torphy, R. J., Steiger, K., Hongo, H., Ritchie, A. J., Kriegsmann, M., Horst, D., Umetsu, S. E., Joseph, N. M., McGregor, K., et al. (2020) · Journal of Clinical Investigation

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 127

Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application

Echle, A., Ghaffari Laleh, N., Quirke, P., Grabsch, H. I., Muti, H. S., Saldanha, O. L., Brockmoeller, S. F., van den Brandt, P. A., Hutchins, G. G. A., Richman, S. D., et al. (2022) · ESMO Open

AI in cancer detectionGenetic factors in colorectal cancer

Cited by 111

Structure and content of the EU-IVDR: Current status and implications for pathology

Kahles, A., Goldschmid, H., Volckmar, A.-L., Ploeger, C., Kazdal, D., Penzel, R., Budczies, J., Kempny, G., Kazmierczak, M., Flechtenmacher, C., et al. (2023) · Die Pathologie

Healthcare RegulationClinical Laboratory Practices and Quality Control

Cited by 27

RudolfV: A Foundation Model by Pathologists for Pathologists

Dippel, J., Feulner, B., Winterhoff, T., Milbich, T., Tietz, S., Schallenberg, S., Dernbach, G., Kunft, A., Heinke, S., Eich, M.-L., et al. (2024) · arXiv

AI in cancer detectionArtificial Intelligence in Healthcare and Education

Cited by 27

Consensus Molecular Subtypes as Biomarkers of Fluorouracil and Folinic Acid Maintenance Therapy With or Without Panitumumab in RAS Wild-Type Metastatic Colorectal Cancer (PanaMa, AIO KRK 0212)

Stahler, A., Hoppe, B., Na, I.-K., Keilholz, L., Müller, L., Karthaus, M., Fruehauf, S., Graeven, U., Fischer von Weikersthal, L., Goekkurt, E., et al. (2023) · Journal of Clinical Oncology

Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments

Cited by 16