Gassenhuber, Johann

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Bossart, M., Wagner, M., Elvert, R., Evers, A., Hübschle, T., Kloeckener, T., Lorenz, K., Moessinger, C., Eriksson, O., Velikyan, I., et al. (2022) · Cell Metabolism

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 179

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., et al. (2023) · Nature Biotechnology

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 111

Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels

Petrera, A., Gassenhuber, J., Ruf, S., Gunasekaran, D., Esser, J., Shahinian, J. H., Hübschle, T., Rütten, H., Sadowski, T., & Schilling, O. (2016) · Journal of Translational Medicine

Cardiac Fibrosis and RemodelingProtease and Inhibitor Mechanisms

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Proteomic Profiling of Cardiomyocyte-Specific Cathepsin A Overexpression Links Cathepsin A to the Oxidative Stress Response

Petrera, A., Kern, U., Linz, D., Gomez-Auli, A., Hohl, M., Gassenhuber, J., Sadowski, T., & Schilling, O. (2016) · Journal of Proteome Research

Protease and Inhibitor MechanismsUbiquitin and proteasome pathways

Cited by 22

The effect of GLP-1 receptor agonist lixisenatide on experimental diabetic retinopathy

Oezer, K., Kolibabka, M., Gassenhuber, J., Dietrich, N., Fleming, T., Schlotterer, A., Morcos, M., Wohlfart, P., & Hammes, H.-P. (2023) · Acta Diabetologica

Retinal Diseases and TreatmentsDiabetes Treatment and Management

Cited by 22