D’Alessio, David A.
Duke Medical Center
26 papers on CoChatORCID 0000-0003-4155-4870
Most cited papers
- Verified
Management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the american diabetes association (ADA) and the european association for the study of diabetes (EASD)
Davies, M. J., D’Alessio, D. A., Fradkin, J., Kernan, W. N., Mathieu, C., Mingrone, G., Rossing, P., Tsapas, A., Wexler, D. J., & Buse, J. B. (2018) · Diabetes Care
Diabetes Treatment and ManagementDiabetes Management and Research
Cited by 3,518
- Verified
Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Davies, M. J., D’Alessio, D. A., Fradkin, J., Kernan, W. N., Mathieu, C., Mingrone, G., Rossing, P., Tsapas, A., Wexler, D. J., & Buse, J. B. (2018) · Diabetologia
Diabetes Treatment and ManagementDiabetes Management and Research
Cited by 1,455
- Verified
2019 update to: management of hyperglycemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Buse, J. B., Wexler, D. J., Tsapas, A., Rossing, P., Mingrone, G., Mathieu, C., D’Alessio, D. A., & Davies, M. J. (2020) · Diabetes Care
Diabetes Treatment and ManagementDiabetes Management and Research
Cited by 1,192
- Verified
A Randomized Trial Comparing a Very Low Carbohydrate Diet and a Calorie-Restricted Low Fat Diet on Body Weight and Cardiovascular Risk Factors in Healthy Women
Brehm, B. J., Seeley, R. J., Daniels, S. R., & D’Alessio, D. A. (2003) · The Journal of Clinical Endocrinology & Metabolism
Diet and metabolism studiesDietary Effects on Health
Cited by 830
- Verified
Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis
Falciglia, M., Freyberg, R. W., Almenoff, P. L., D’Alessio, D. A., & Render, M. L. (2009) · Critical Care Medicine
Hyperglycemia and glycemic control in critically ill and hospitalized patientsDiabetes Management and Research
Cited by 576
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Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M. B. N., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., et al. (2020) · JCI Insight
Diabetes Treatment and ManagementReceptor Mechanisms and Signaling
Cited by 541
- Verified
2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Buse, J. B., Wexler, D. J., Tsapas, A., Rossing, P., Mingrone, G., Mathieu, C., D’Alessio, D. A., & Davies, M. J. (2020) · Diabetologia
Diabetes Treatment and ManagementDiabetes Management and Research
Cited by 487
- Verified
Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status
Drazen, D. L., Vahl, T. P., D’Alessio, D. A., Seeley, R. J., & Woods, S. C. (2006) · Endocrinology
Regulation of Appetite and ObesityHypothalamic control of reproductive hormones
Cited by 334
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Gastric Bypass Surgery Enhances Glucagon-Like Peptide 1–Stimulated Postprandial Insulin Secretion in Humans
Salehi, M., Prigeon, R. L., & D’Alessio, D. A. (2011) · Diabetes
Bariatric Surgery and OutcomesPancreatic function and diabetes
Cited by 323
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Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
Vahl, T. P., Tauchi, M., Durler, T. S., Elfers, E. E., Fernandes, T. M., Bitner, R. D., Ellis, K. S., Woods, S. C., Seeley, R. J., Herman, J. P., et al. (2007) · Endocrinology
Diabetes Treatment and ManagementRegulation of Appetite and Obesity
Cited by 318
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Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions
Habegger, K. M., Stemmer, K., Cheng, C., Müller, T. D., Heppner, K. M., Ottaway, N., Holland, J., Hembree, J. L., Smiley, D., Gelfanov, V., et al. (2013) · Diabetes
Fibroblast Growth Factor ResearchPancreatic function and diabetes
Cited by 245
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Cardiovascular outcomes with tirzepatide versus dulaglutide in type 2 diabetes
Nicholls, S. J., Pavo, I., Bhatt, D. L., Buse, J. B., Del Prato, S., Kahn, S. E., Lincoff, A. M., McGuire, D. K., Miller, D., Nauck, M. A., et al. (2025) · New England Journal of Medicine
Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 223
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LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial
Urva, S., Coskun, T., Loh, M. T., Du, Y., Thomas, M. K., Gurbuz, S., Haupt, A., Benson, C. T., Hernandez-Illas, M., D’Alessio, D. A., et al. (2022) · The Lancet
Diabetes Treatment and ManagementDiabetes Management and Research
Cited by 202
- Verified
One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes
Brehm, B. J., Lattin, B. L., Summer, S. S., Boback, J. A., Gilchrist, G. M., Jandacek, R. J., & D’Alessio, D. A. (2009) · Diabetes Care
Diet and metabolism studiesNutritional Studies and Diet
Cited by 196
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Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans
Koska, J., Sands, M., Burciu, C., D’Souza, K. M., Raravikar, K., Liu, J., Truran, S., Franco, D. A., Schwartz, E. A., Schwenke, D. C., et al. (2015) · Diabetes
Diabetes Treatment and ManagementNitric Oxide and Endothelin Effects
Cited by 174
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Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1c targets
DeVries, J. H., Bain, S. C., Rodbard, H. W., Seufert, J., D’Alessio, D., Thomsen, A. B., Zychma, M., Rosenstock, J., & on behalf of the Liraglutide-Detemir Study Group (2012) · Diabetes Care
Diabetes Treatment and ManagementDiabetes Management and Research
Cited by 159
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GIPR/GLP-1R dual agonist therapies for diabetes and weight loss—chemistry, physiology, and clinical applications
Campbell, J. E., Müller, T. D., Finan, B., DiMarchi, R. D., Tschöp, M. H., & D’Alessio, D. A. (2023) · Cell Metabolism
Diabetes Treatment and ManagementPancreatic function and diabetes
Cited by 149
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Psyllium fiber improves glycemic control proportional to loss of glycemic control: A meta-analysis of data in euglycemic subjects, patients at risk of type 2 diabetes mellitus, and patients being treated for type 2 diabetes mellitus
Gibb, R. D., McRorie, J. W., Russell, D. A., Hasselblad, V., & D’Alessio, D. A. (2015) · The American Journal of Clinical Nutrition
Food composition and propertiesDiabetes Treatment and Management
Cited by 144
- Verified
GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells
El, K., Gray, S. M., Capozzi, M. E., Knuth, E. R., Jin, E., Svendsen, B., Clifford, A., Brown, J. L., Encisco, S. E., Chazotte, B. M., et al. (2021) · Science Advances
Pancreatic function and diabetesDiabetes Treatment and Management
Cited by 132
- Verified
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
El, K., Douros, J. D., Willard, F. S., Novikoff, A., Sargsyan, A., Perez-Tilve, D., Wainscott, D. B., Yang, B., Chen, A., Wothe, D., et al. (2023) · Nature Metabolism
Pancreatic function and diabetesDiabetes Treatment and Management
Cited by 118
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Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans
Quddusi, S., Vahl, T. P., Hanson, K., Prigeon, R. L., & D’Alessio, D. A. (2003) · Diabetes Care
Diabetes Treatment and ManagementPancreatic function and diabetes
Cited by 111
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β-Cell Function, Insulin Sensitivity, and Glucose Tolerance in Obese Diabetic and Nondiabetic Adolescents and Young Adults
Elder, D. A., Prigeon, R. L., Wadwa, R. P., Dolan, L. M., & D’Alessio, D. A. (2006) · The Journal of Clinical Endocrinology & Metabolism
Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins
Cited by 78
- Verified
Effect of Glycemia on Plasma Incretins and the Incretin Effect During Oral Glucose Tolerance Test
Salehi, M., Aulinger, B., & D’Alessio, D. A. (2012) · Diabetes
Diabetes Treatment and ManagementPancreatic function and diabetes
Cited by 38
- Verified
Slow and Steady Wins the Race: 25 Years Developing the GLP-1 Receptor as an Effective Target for Weight Loss
Kumar, N., & D’Alessio, D. A. (2022) · The Journal of Clinical Endocrinology & Metabolism
Regulation of Appetite and ObesityPharmacology and Obesity Treatment
Cited by 14
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