Chiang, Gary G.
eFFECTOR Therapeutics (United States)
8 papers on CoChatORCID 0000-0003-3004-7400
Most cited papers
- Verified
Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin
Hudson, C. C., Liu, M., Chiang, G. G., Otterness, D. M., Loomis, D. C., Kaper, F., Giaccia, A. J., & Abraham, R. T. (2002) · Molecular and Cellular Biology
Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer
Cited by 1,186
- Verified
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Lasko, L. M., Jakob, C. G., Edalji, R. P., Qiu, W., Montgomery, D., Digiammarino, E. L., Hansen, T. M., Risi, R. M., Frey, R., Manaves, V., et al. (2017) · Nature
Histone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors
Cited by 858
- Verified
Comparative Metabolic Flux Profiling of Melanoma Cell Lines
Scott, D. A., Richardson, A. D., Filipp, F. V., Knutzen, C. A., Chiang, G. G., Ronai, Z. A., Osterman, A. L., & Smith, J. W. (2011) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 328
- Verified
The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex
He, Y., Selvaraju, S., Curtin, M. L., Jakob, C. G., Zhu, H., Comess, K. M., Shaw, B., The, J., Lima-Fernandes, E., Szewczyk, M. M., et al. (2017) · Nature Chemical Biology
Epigenetics and DNA MethylationCancer-related gene regulation
Cited by 224
- Verified
Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a
Sweis, R. F., Pliushchev, M., Brown, P. J., Guo, J., Li, F., Maag, D., Petros, A. M., Soni, N. B., Tse, C., Vedadi, M., et al. (2014) · ACS Medicinal Chemistry Letters
Epigenetics and DNA MethylationCancer-related gene regulation
Cited by 193
- Verified
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase
Ernst, J. T., Thompson, P. A., Nilewski, C., Sprengeler, P. A., Sperry, S., Packard, G., Michels, T., Xiang, A., Tran, C., Wegerski, C. J., et al. (2020) · Journal of Medicinal Chemistry
RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer
Cited by 150
- Verified
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase
Katiyar, S., Liu, E., Knutzen, C. A., Lang, E. S., Lombardo, C. R., Sankar, S., Toth, J. I., Petroski, M. D., Ronai, Z., & Chiang, G. G. (2009) · The EMBO Reports
PI3K/AKT/mTOR signaling in cancerUbiquitin and proteasome pathways
Cited by 150
- Verified
Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A
Thompson, P. A., Eam, B., Young, N. P., Fish, S., Chen, J., Barrera, M., Howard, H., Sung, E., Parra, A., Staunton, J., et al. (2021) · Molecular Cancer Therapeutics
PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms
Cited by 50
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