Schenk, Simon

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Milne, J. C., Lambert, P. D., Schenk, S., Carney, D. P., Smith, J. J., Gagne, D. J., Jin, L., Boss, O., Perni, R. B., Vu, C. B., et al. (2007) · Nature

Sirtuins and Resveratrol in MedicineNatural Antidiabetic Agents Studies

Cited by 1,707

Insulin sensitivity: Modulation by nutrients and inflammation

Schenk, S., Saberi, M., & Olefsky, J. M. (2008) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,191

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

Lee, Y. S., Kim, J.-W., Osborne, O., Oh, D. Y., Sasik, R., Schenk, S., Chen, A., Chung, H., Murphy, A., Watkins, S. M., et al. (2014) · Cell

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 598

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

Saberi, M., Woods, N.-B., de Luca, C., Schenk, S., Lu, J. C., Bandyopadhyay, G., Verma, I. M., & Olefsky, J. M. (2009) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 456

Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid–induced insulin resistance

Schenk, S., & Horowitz, J. F. (2007) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 407

Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

Ribas, V., Drew, B. G., Zhou, Z., Phun, J., Kalajian, N. Y., Soleymani, T., Daraei, P., Widjaja, K., Wanagat, J., de Aguiar Vallim, T. Q., et al. (2016) · Science Translational Medicine

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 259

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction

Schenk, S., McCurdy, C. E., Philp, A., Chen, M. Z., Holliday, M. J., Bandyopadhyay, G. K., Osborn, O., Baar, K., & Olefsky, J. M. (2011) · Journal of Clinical Investigation

Sirtuins and Resveratrol in MedicineMetabolism, Diabetes, and Cancer

Cited by 197

Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation following Endurance Exercise

Philp, A., Chen, A., Lan, D., Meyer, G. A., Murphy, A. N., Knapp, A. E., Olfert, I. M., McCurdy, C. E., Marcotte, G. R., Hogan, M. C., et al. (2011) · Journal of Biological Chemistry

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 184

Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training

Schenk, S., & Horowitz, J. F. (2006) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 108

Unraveling the Complexities of SIRT1-Mediated Mitochondrial Regulation in Skeletal Muscle

Philp, A., & Schenk, S. (2013) · Exercise and Sport Sciences Reviews

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 39