Elia, Andrew J.

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Harris, I. S., Treloar, A. E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K. C., Yung, K. Y., Brenner, D., Knobbe-Thomsen, C. B., Cox, M. A., et al. (2015) · Cancer Cell

Redox biology and oxidative stressGlutathione Transferases and Polymorphisms

Cited by 993

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

de la Pompa, J. L., Timmerman, L. A., Takimoto, H., Yoshida, H., Elia, A. J., Samper, E., Potter, J., Wakeham, A., Marengere, L., Langille, B. L., et al. (1998) · Nature

Congenital heart defects researchSignaling Pathways in Disease

Cited by 660

The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses

Suh, W.-K., Gajewska, B. U., Okada, H., Gronski, M. A., Bertram, E. M., Dawicki, W., Duncan, G. S., Bukczynski, J., Plyte, S., Elia, A., et al. (2003) · Nature Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 576

Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development

Yeh, W.-C., Itie, A., Elia, A. J., Ng, M., Shu, H.-B., Wakeham, A., Mirtsos, C., Suzuki, N., Bonnard, M., Goeddel, D. V., et al. (2000) · Immunity

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 515

Severe liver degeneration and lack of NF-κ B activation in NEMO/IKKγ-deficient mice

Rudolph, D., Yeh, W.-C., Wakeham, A., Rudolph, B., Nallainathan, D., Potter, J., Elia, A. J., & Mak, T. W. (2000) · Genes & Development

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 479

Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury

Berger, T., Togawa, A., Duncan, G. S., Elia, A. J., You-Ten, A., Wakeham, A., Fong, H. E. H., Cheung, C. C., & Mak, T. W. (2006) · Proceedings of the National Academy of Sciences

Inflammation biomarkers and pathwaysAntimicrobial Peptides and Activities

Cited by 460

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

Sasaki, M., Knobbe, C. B., Itsumi, M., Elia, A. J., Harris, I. S., Chio, I. I. C., Cairns, R. A., McCracken, S., Wakeham, A., Haight, J., et al. (2012) · Genes & Development

Cancer, Hypoxia, and MetabolismGlioma Diagnosis and Treatment

Cited by 296

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

Gorrini, C., Baniasadi, P. S., Harris, I. S., Silvester, J., Inoue, S., Snow, B., Joshi, P. A., Wakeham, A., Molyneux, S. D., Martin, B., et al. (2013) · Journal of Experimental Medicine

Genomics, phytochemicals, and oxidative stressBRCA gene mutations in cancer

Cited by 289

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

Cox, M. A., Duncan, G. S., Lin, G. H. Y., Steinberg, B. E., Yu, L. X., Brenner, D., Buckler, L. N., Elia, A. J., Wakeham, A. C., Nieman, B., et al. (2019) · Science

T-cell and B-cell ImmunologyVagus Nerve Stimulation Research

Cited by 155

Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis

Berger, T., Cheung, C. C., Elia, A. J., & Mak, T. W. (2010) · Proceedings of the National Academy of Sciences

Protease and Inhibitor MechanismsMechanisms of cancer metastasis

Cited by 96

Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma

Zheng, C., Snow, B. E., Elia, A. J., Nechanitzky, R., Dominguez-Brauer, C., Liu, S., Tong, Y., Cox, M. A., Focaccia, E., Wakeham, A. C., et al. (2023) · Nature Cancer

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 75