Drenth, Joost P.H.

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis

Nevens, F., Andreone, P., Mazzella, G., Strasser, S. I., Bowlus, C., Invernizzi, P., Drenth, J. P. H., Pockros, P. J., Regula, J., Beuers, U., et al. (2016) · New England Journal of Medicine

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 1,131

Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

Ratziu, V., Harrison, S. A., Francque, S., Bedossa, P., Lehert, P., Serfaty, L., Romero-Gomez, M., Boursier, J., Abdelmalek, M., Caldwell, S., et al. (2016) · Gastroenterology

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 1,035

Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis: Boonstra et al.

Boonstra, K., Weersma, R. K., van Erpecum, K. J., Rauws, E. A., Spanier, B. W. M., Poen, A. C., van Nieuwkerk, K. M., Drenth, J. P., Witteman, B. J., Tuynman, H. A., et al. (2013) · Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 725

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis

Rosendahl, J., Witt, H., Szmola, R., Bhatia, E., Ózsvári, B., Landt, O., Schulz, H.-U., Gress, T. M., Pfützer, R., Löhr, M., et al. (2008) · Nature Genetics

Pancreatitis Pathology and TreatmentPancreatic and Hepatic Oncology Research

Cited by 439

Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1

de Boer, Y. S., van Gerven, N. M. F., Zwiers, A., Verwer, B. J., van Hoek, B., van Erpecum, K. J., Beuers, U., van Buuren, H. R., Drenth, J. P. H., den Ouden, J. W., et al. (2014) · Gastroenterology

Liver Diseases and ImmunityGenetic Associations and Epidemiology

Cited by 304

Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease

Drenth, J. P. H., te Morsche, R. H. M., Smink, R., Bonifacino, J. S., & Jansen, J. B. M. J. (2003) · Nature Genetics

Genetic and Kidney Cyst DiseasesPediatric Hepatobiliary Diseases and Treatments

Cited by 234

Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial

de Vries, E., Bolier, R., Goet, J., Parés, A., Verbeek, J., de Vree, M., Drenth, J., van Erpecum, K., van Nieuwkerk, K., van der Heide, F., et al. (2021) · Gastroenterology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 224

Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: a multicenter, randomized, double-blind, placebo-controlled phase II trial

Hirschfield, G. M., Chazouillères, O., Drenth, J. P., Thorburn, D., Harrison, S. A., Landis, C. S., Mayo, M. J., Muir, A. J., Trotter, J. F., Leeming, D. J., et al. (2019) · Journal of Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 187

Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study

Trauner, M., Nevens, F., Shiffman, M. L., Drenth, J. P. H., Bowlus, C. L., Vargas, V., Andreone, P., Hirschfield, G. M., Pencek, R., Malecha, E. S., et al. (2019) · The Lancet Gastroenterology & Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 180

Patients with isolated polycystic liver disease referred to liver centres: Clinical characterization of 137 cases

Van Keimpema, L., De Koning, D. B., Van Hoek, B., Van Den Berg, A. P., Van Oijen, M. G. H., De Man, R. A., Nevens, F., & Drenth, J. P. H. (2011) · Liver International

Genetic and Kidney Cyst DiseasesTuberous Sclerosis Complex Research

Cited by 152

Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study

Hirschfield, G. M., Shiffman, M. L., Gulamhusein, A., Kowdley, K. V., Vierling, J. M., Levy, C., Kremer, A. E., Zigmond, E., Andreone, P., Gordon, S. C., et al. (2023) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 127

Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis

Cnossen, W. R., te Morsche, R. H. M., Hoischen, A., Gilissen, C., Chrispijn, M., Venselaar, H., Mehdi, S., Bergmann, C., Veltman, J. A., & Drenth, J. P. H. (2014) · Proceedings of the National Academy of Sciences

Genetic and Kidney Cyst DiseasesGenomics and Rare Diseases

Cited by 90

Extensive mutational analysis ofPRKCSH andSEC63 broadens the spectrum of polycystic liver disease

Waanders, E., te Morsche, R. H. M., de Man, R. A., Jansen, J. B. M. J., & Drenth, J. P. H. (2006) · Human Mutation

Genetic and Kidney Cyst DiseasesTuberous Sclerosis Complex Research

Cited by 64

Congenital disorders of glycosylation in hepatology: The example of polycystic liver disease

Janssen, M. J., Waanders, E., Woudenberg, J., Lefeber, D. J., & Drenth, J. P. H. (2010) · Journal of Hepatology

Genetic and Kidney Cyst DiseasesGlycogen Storage Diseases and Myoclonus

Cited by 54

Risk of gallbladder cancer in patients with primary sclerosing cholangitis and radiographically detected gallbladder polyps

van Erp, L. W., Cunningham, M., Narasimman, M., Ale Ali, H., Jhaveri, K., Drenth, J. P. H., Janssen, H. L. A., Levy, C., Hirschfield, G. M., Hansen, B. E., et al. (2020) · Liver International

Cholangiocarcinoma and Gallbladder Cancer StudiesLiver Diseases and Immunity

Cited by 46

Assessment of histological remission in ulcerative colitis: discrepancies between daily practice and expert opinion

Römkens, T. E. H., Kranenburg, P., Tilburg, A. V., Bronkhorst, C., Nagtegaal, I. D., Drenth, J. P. H., & Hoentjen, F. (2018) · Journal of Crohn's and Colitis

Inflammatory Bowel DiseaseMicroscopic Colitis

Cited by 36

Low Yield for Routine Laboratory Checks in Follow-up of Coeliac Disease

Burger, J. P., Van der Laan, J. J., Jansen, T. A., Drenth, J. P., Roovers, E. A., Wessels, M. M., & Wahab, P. J. (2018) · Journal of Gastrointestinal and Liver Diseases

Celiac Disease Research and ManagementEosinophilic Esophagitis

Cited by 19