Gurnell, Mark

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

Barroso, I., Gurnell, M., Crowley, V. E. F., Agostini, M., Schwabe, J. W., Soos, M. A., Maslen, G. L., Williams, T. D. M., Lewis, H., Schafer, A. J., et al. (1999) · Nature

Peroxisome Proliferator-Activated ReceptorsMetabolism, Diabetes, and Cancer

Cited by 1,368

Whole-genome sequencing of patients with rare diseases in a national health system

Turro, E., Astle, W. J., Megy, K., Gräf, S., Greene, D., Shamardina, O., Allen, H. L., Sanchis-Juan, A., Frontini, M., Thys, C., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 554

Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society International Consensus Statement

Petersenn, S., Fleseriu, M., Casanueva, F. F., Giustina, A., Biermasz, N., Biller, B. M. K., Bronstein, M., Chanson, P., Fukuoka, H., Gadelha, M., et al. (2023) · Nature Reviews Endocrinology

Pituitary Gland Disorders and TreatmentsNeuroendocrine Tumor Research Advances

Cited by 411

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

Schoenmakers, E., Agostini, M., Mitchell, C., Schoenmakers, N., Papp, L., Rajanayagam, O., Padidela, R., Ceron-Gutierrez, L., Doffinger, R., Prevosto, C., et al. (2010) · Journal of Clinical Investigation

Selenium in Biological SystemsOrganoselenium and organotellurium chemistry

Cited by 315

Pitfalls in the measurement and interpretation of thyroid function tests

Koulouri, O., Moran, C., Halsall, D., Chatterjee, K., & Gurnell, M. (2013) · Best Practice & Research Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsClinical Laboratory Practices and Quality Control

Cited by 282

Effectiveness of metyrapone in treating Cushing's syndrome: a retrospective multicenter study in 195 patients

Daniel, E., Aylwin, S., Mustafa, O., Ball, S., Munir, A., Boelaert, K., Chortis, V., Cuthbertson, D. J., Daousi, C., Rajeev, S. P., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 231

Evaluation of the Sensitivity and Specificity of 11 C-Metomidate Positron Emission Tomography (PET)-CT for Lateralizing Aldosterone Secretion by Conn's Adenomas

Burton, T. J., Mackenzie, I. S., Balan, K., Koo, B., Bird, N., Soloviev, D. V., Azizan, E. A. B., Aigbirhio, F., Gurnell, M., & Brown, M. J. (2012) · The Journal of Clinical Endocrinology & Metabolism

Hormonal Regulation and HypertensionAdrenal and Paraganglionic Tumors

Cited by 226

Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

Okosieme, O., Gilbert, J., Abraham, P., Boelaert, K., Dayan, C., Gurnell, M., Leese, G., McCabe, C., Perros, P., Smith, V., et al. (2016) · Clinical Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 208

Oral corticosteroid elimination via a personalised reduction algorithm in adults with severe, eosinophilic asthma treated with benralizumab (PONENTE): a multicentre, open-label, single-arm study

Menzies-Gow, A., Gurnell, M., Heaney, L. G., Corren, J., Bel, E. H., Maspero, J., Harrison, T., Jackson, D. J., Price, D., Lugogo, N., et al. (2022) · The Lancet Respiratory Medicine

Asthma and respiratory diseasesAdrenal Hormones and Disorders

Cited by 177

Resistance to thyroid hormone caused by a mutation in thyroid hormone receptor (TR)α1 and TRα2: clinical, biochemical, and genetic analyses of three related patients

Moran, C., Agostini, M., Visser, W. E., Schoenmakers, E., Schoenmakers, N., Offiah, A. C., Poole, K., Rajanayagam, O., Lyons, G., Halsall, D., et al. (2014) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 127

Interoceptive Ability Predicts Survival on a London Trading Floor

Kandasamy, N., Garfinkel, S. N., Page, L., Hardy, B., Critchley, H. D., Gurnell, M., & Coates, J. M. (2016) · Scientific Reports

Heart Rate Variability and Autonomic ControlDecision-Making and Behavioral Economics

Cited by 121

Expert Consensus on the Tapering of Oral Corticosteroids for the Treatment of Asthma. A Delphi Study

Suehs, C. M., Menzies-Gow, A., Price, D., Bleecker, E. R., Canonica, G. W., Gurnell, M., & Bourdin, A. (2021) · American Journal of Respiratory and Critical Care Medicine

Asthma and respiratory diseasesAdrenal Hormones and Disorders

Cited by 118

The screening and management of pituitary dysfunction following traumatic brain injury in adults: British Neurotrauma Group guidance

Tan, C. L., Alavi, S. A., Baldeweg, S. E., Belli, A., Carson, A., Feeney, C., Goldstone, A. P., Greenwood, R., Menon, D. K., Simpson, H. L., et al. (2017) · Journal of Neurology, Neurosurgery & Psychiatry

Pituitary Gland Disorders and TreatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 111

What should be done when thyroid function tests do not make sense?: Atypical thyroid function tests

Gurnell, M., Halsall, D. J., & Chatterjee, V. K. (2011) · Clinical Endocrinology

Thyroid Disorders and TreatmentsClinical Laboratory Practices and Quality Control

Cited by 88

11C‐Metomidate PET/CT is a useful adjunct for lateralization of primary aldosteronism in routine clinical practice

O’Shea, P. M., O’Donoghue, D., Bashari, W., Senanayake, R., Joyce, M. B., Powlson, A. S., Browne, D., O’Sullivan, G. J., Cheow, H., Mendichovszky, I., et al. (2019) · Clinical Endocrinology

Hormonal Regulation and HypertensionAdrenal and Paraganglionic Tumors

Cited by 58

A Novel Thyrotropin-Releasing Hormone Receptor Missense Mutation (P81R) in Central Congenital Hypothyroidism

Koulouri, O., Nicholas, A. K., Schoenmakers, E., Mokrosinski, J., Lane, F., Cole, T., Kirk, J., Farooqi, I. S., Chatterjee, V. K., Gurnell, M., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 32

A novel IGSF 1 mutation in a large Irish kindred highlights the need for familial screening in the IGSF 1 deficiency syndrome

Roche, E. F., McGowan, A., Koulouri, O., Turgeon, M., Nicholas, A. K., Heffernan, E., El‐Khairi, R., Abid, N., Lyons, G., Halsall, D., et al. (2018) · Clinical Endocrinology

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 29