Skarnes, William C.

A conditional knockout resource for the genome-wide study of mouse gene function

Skarnes, W. C., Rosen, B., West, A. P., Koutsourakis, M., Bushell, W., Iyer, V., Mujica, A. O., Thomas, M., Harrow, J., Cox, T., et al. (2011) · Nature

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 1,708

Functional analysis of secreted and transmembrane proteins critical to mouse development.

Mitchell, K. J., Pinson, K. I., Kelly, O. G., Brennan, J., Zupicich, J., Scherz, P., Leighton, P. A., Goodrich, L. V., Lu, X., Avery, B. J., et al. (2001) · Nature Genetics

Animal Genetics and ReproductionDevelopmental Biology and Gene Regulation

Cited by 400

A reference human induced pluripotent stem cell line for large-scale collaborative studies

Pantazis, C. B., Yang, A., Lara, E., McDonough, J. A., Blauwendraat, C., Peng, L., Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., et al. (2022) · Cell Stem Cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 310

Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform

Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S. A., George, V., Kalra, S., Kondrashov, A., Hoang, M. D., Mosqueira, D., Patel, A., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 293

Off-target mutations are rare in Cas9-modified mice

Iyer, V., Shen, B., Zhang, W., Hodgkins, A., Keane, T., Huang, X., & Skarnes, W. C. (2015) · Nature Methods

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 185

Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4

Stephenson, R. A., Sepulveda, J., Johnson, K. R., Lita, A., Gopalakrishnan, J., Acri, D. J., Beilina, A., Cheng, L., Yang, L. G., Root, J. T., et al. (2025) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsLipid metabolism and biosynthesis

Cited by 55