Mazur, Curt

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

Polymenidou, M., Lagier-Tourenne, C., Hutt, K. R., Huelga, S. C., Moran, J., Liang, T. Y., Ling, S.-C., Sun, E., Wancewicz, E., Mazur, C., et al. (2011) · Nature Neuroscience

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

Cited by 1,335

Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

Kordasiewicz, H. B., Stanek, L. M., Wancewicz, E. V., Mazur, C., McAlonis, M. M., Pytel, K. A., Artates, J. W., Weiss, A., Cheng, S. H., Shihabuddin, L. S., et al. (2012) · Neuron

Genetic Neurodegenerative DiseasesRNA Interference and Gene Delivery

Cited by 770

Lactate inhibits lipolysis in fat cells through activation of an orphan g-protein-coupled receptor, gpr81

Liu, C., Wu, J., Zhu, J., Kuei, C., Yu, J., Shelton, J., Sutton, S. W., Li, X., Yun, S. J., Mirzadegan, T., et al. (2009) · Journal of Biological Chemistry

Adipose Tissue and MetabolismReceptor Mechanisms and Signaling

Cited by 606

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration

Jafar-nejad, P., Powers, B., Soriano, A., Zhao, H., Norris, D. A., Matson, J., DeBrosse-Serra, B., Watson, J., Narayanan, P., Chun, S. J., et al. (2021) · Nucleic Acids Research

RNA Interference and Gene DeliveryNeurogenetic and Muscular Disorders Research

Cited by 128

Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging

Mazur, C., Powers, B., Zasadny, K., Sullivan, J. M., Dimant, H., Kamme, F., Hesterman, J., Matson, J., Oestergaard, M., Seaman, M., et al. (2019) · JCI Insight

RNA Interference and Gene DeliveryNeurogenetic and Muscular Disorders Research

Cited by 114